Cas No.: | 2407860-34-6 |
Chemical Name: | (S)-ErSO |
SMILES: | O=C1NC2=C(C=CC=C2C(F)(F)F)[C@]1(C3=CC=C(O)C=C3)C4=CC=C(OC(F)(F)F)C=C4 |
Formula: | C22H13F6NO3 |
M.Wt: | 453.33 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Publication: | [1]. David J. Shapiro, et al. Activators of the unfolded protein response. WO2020009958A1. |
Description: | (S)-ErSO is the dextrorotatory enantiomer of ErSO. (S)-ErSO is inactive in MCF-7 cells (from patent WO2020009958A1, compound (s)-105)[1]. |
In Vitro: | (-)-ErSO induces dose-dependent death of MCF-7 cells; (+)-l05 is inactive[1]. |
References: | [1]. David J. Shapiro, et al. Activators of the unfolded protein response. WO2020009958A1. |