Saframycin D|CAS 66082-30-2|DC Chemicals

Cas No.:	66082-30-2
Chemical Name:	Saframycin D
SMILES:	CN1[C@@]2([H])[C@@]3([H])N(C[C@]1([H])C(C4=C(O)C(C)=C(OC)C(O)=C42)=O)[C@H](C5=C(C(C(C)=C(C5=O)OC)=O)C3)CNC(C(C)=O)=O
Formula:	C₂₈H₃₁N₃O₉
M.Wt:	553.56
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

Cat. No.	Product name	Field of application
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DC72568	Cymal-6	Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) is a potent TEM-1 beta-lactamase inhibitor with an Ki value of 40.05 µM. Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) can be used as glycosidic surfactant.
DC72280	PNU-101603	PNU-101603 is a metabolite of Sutezolid. PNU-101603 has excellent activity against Mycobacterium tuberculosis (MTB).
DC72279	MRV03-070	MRV03-070 is an inhibitor of colibactin-activating peptidase ClbP with an IC50 value of 69 nM, acts like biosynthetic precursor precolibactin.
DC72144	TH-Z145	TH-Z145, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 210 nM).
DC72008	UNC10201652	UNC10201652 is a potent Loop 1 (L1)-specific gut bacterial β-glucuronidase (GUSs) inhibitor with an IC50 value of 0.117 μM for E. coli GUS. UNC10201652 can block SN-38 glucuronide processing only in individuals whose fecal gut microbiota is highly abundant in L1 GUS enzymes.
DC71474	VP-4604	VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) agent. VP-4604 exhibits significant microbial growth inhibition toward Staphylococcus aureus (ATCC 43300) with MIC of 4-8 µg/mL. VP-4604 inhibits the growth of methicillin‐resistant Staphylococcus aureus with growth inhibition >95%.
DC71466	EDA-DA	EDA-DA is an unnatural dipeptide building block (an ethynyl-D-alanine and a D-alanine). It incorporates a biorthogonal alkyne group into peptidoglycan (PG) through MurF in the cytoplasmic pathway, which enables selective labeling via a click-chemistry reaction. EDA-DA allows labeling of PG in Gram-positive (B. subtilis), Gram-negative (E. coli and C. trachomatis), Mycobacterium (M. smegmatis) and moss plastids (P. patens) with azide modified fluorescent dyes such as Alexa Fluor 488.