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MU262

  Cat. No.:  DC81092  
Chemical Structure
1823291-67-3
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More than 5000 active chemicals with high quality for research!
Field of application
MU262 is a MUS81 inhibitor with an IC50 value of 0.87 μM. MU262 directly inhibits the catalytic activity of MUS81 without interfering with DNA binding, induces genomic instability in tumor cells, and specifically inhibits the HR/BIR repair pathway. The combination of MU262 with Cisplatin significantly enhances the chemotherapeutic killing effect. MU262 serves as a chemical biology tool for studying MUS81 function, and also acts as a lead compound for the development of anticancer therapies that exploit DNA repair defects in cancer cells.
Cas No.: 1823291-67-3
Chemical Name: MU262
Formula: C18H28N2O4
M.Wt: 336.43
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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