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TP0586532

  Cat. No.:  DC46373   Featured
Chemical Structure
2427584-96-9
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More than 5000 active chemicals with high quality for research!
Field of application
TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2427584-96-9
Chemical Name: TP0586532
SMILES: C[C@H](O)C1=NC=CN1CC2=NOC(C(C=C3)=CC=C3C#C[C@H]4[C@@]5([H])[C@]4([H])CN(C5)CCCC(O)=O)=C2
Formula: C26H28N4O4
M.Wt: 460.52
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].
Target: IC50: 0.101 μM (non-hydroxamate LpxC)[1]
In Vitro: TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].
References: [1]. Ushiyama F, et al. Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg Med Chem. 2021;30:115964.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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