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Cell Cycle/DNA Damage

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Cat. No. Product Name Field of Application Chemical Structure
DC76245 ARCher-142
ARCher-142 (compound S8) is a potent tankyrase inhibitor. ARCher-142 selectively binds to ARC4 with potency of 8 µM.
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DC76244 (rac)-Talazoparib
(rac)-Talazoparib ((rac)-BMN-673) (Compound 47) is the orally active inhibitor for PARP1/2 with Ki of 1.2 nM and 0.87 nM. (rac)-Talazoparib inhibits cellular PARylation with an EC50 of 2.51 nM. (rac)-Talazoparib causes the accumulation of DNA damage, inhibits proliferation of BRCA1/2-mutated MX-1 cell and Capan-1 cell with IC50 of 0.3 nM and 5 nM. (rac)-Talazoparib exhibits antitumor efficacy in mouse models.
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DC76243 UnyLinker 12 TEA
UnyLinker 12 TEA is a universal linker that can be used to synthesize oligoribonucleotides.
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DC76242 Ribavirin 5'-monophosphate dilithium
Ribavirin 5'-monophosphate dilithium is an active form of ribavirin that inhibits IMP dehydrogenase, and ribavirin itself is a broad-spectrum antiviral agent.
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DC76241 Pseudouridine 5'-OTBDPS
Pseudouridine 5'-OTBDPS (5-(5-O-TBDPS-β-D-ribofuranosyl)uracil) is an intermediate of Pseudouridine. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
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DC76240 N-Acetyl-2',3'-acetyl-guanosine
N-Acetyl-2', 3'-Acetyl-Guanosine is a modified guanosine nucleoside.
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DC76239 LNA-UTP
LNA-UTP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76238 LNA-GTP
LNA-GTP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76237 LNA-GDP
LNA-GDP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76236 LNA-CTP
LNA-CTP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76235 LNA-ATP
LNA-ATP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76234 LNA-AMP
LNA-AMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76233 Isoorotidine
Isoorotidine is a nucleoside derivative and an isomer of the pyrimidine nucleoside Orotidine, is human erythrocyte acetylcholinesterase (AChE) inhibitor.
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DC76232 DL-Alanosine
DL-Alanosine is an amino acid analogue with antitumor activities.
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DC76231 AA-UTP tetrasodium
AA-UTP tetrasodium is an amine-modified nucleotide that can be directly incorporated into labeled-UTP. DG013B has weak affinity for ERAP1 and ERAP2 and is often used as a negative control to study the binding properties of DG013A and its analogues to ERAP1 and ERAP2.
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DC76230 8-Nitro-2'3'cAMP
8-Nitro-2'3'cAMP is composed of 8-nitro-AMP, ribose and phosphate, and is a cyclic nucleotide derivative.
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DC76229 7-Methylguanosine 5′-monophosphate
7-Methylguanosine 5′-monophosphate (7-Methylguanylic acid) is a building block of nucleic acid.
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DC76228 5-Hydroxycytidine
5-Hydroxycytidine is the RNA modified nucleoside that can be found in the 23S rRNA of bacteria E. coli. 5-Hydroxycytidine modifies at the C2501 site, exhibits a higher modification level in stationary cells. 5-Hydroxycytidine exhibits a higher modification level in radiation resistant Radius than in E. coli.
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DC76227 3'-Deoxy-3'-amino-ATP tetrasodium
3'-Deoxy-3'-amino-ATP tetrasodium is an ATP substitute created by inserting an amino acid at the C3 position of ATP. 3'-Deoxy-3'-amino-ATP tetrasodium catalyzes RNA synthesis in the presence of RNA polymerase.
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DC76226 3'-Amino-3'-dGTP tetrasodium
3'-Amino-3'-dGTP tetrasodium is a substitute for GTP, produced by inserting an amino acid into the C3 position of GTP.
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DC76225 2'-O-MOE-UTP
2'-O-MOE-UTP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76224 2'-O-MOE-GTP
2'-O-MOE-GTP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76223 2'-F-UMP
2'-F-UMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76222 2'-F-CMP
2'-F-CMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76221 2'-F-CDP
2'-F-CDP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76220 2'-F-AMP
2'-F-AMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76219 2'-F-ADP
2'-F-ADP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76218 2-Amino-ATP tetrasodium
2-Amino-ATP tetrasodium is an ATP substitute produced by inserting an amino acid at the C2 position of ATP.
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DC76217 2′-O-MOE-CMP
2′-O-MOE-CMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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DC76216 2′-O-MOE-AMP
2′-O-MOE-AMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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