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| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11856 | MPC-0767 |
MPC-0767 (MPC0767, MPC3100 mesylate hydrate) is an L-alanine ester prodrug of MPC-3100, which is a potent, selective, orally bioavailable Hsp90 inhibitor with IC50 of 0.14 uM.
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| DC11033 | JG-231 |
JG-231 is an allosteric inhibitor that disrupts the Hsp70-BAG3 interaction (Ki=0.11 uM), inhibits breast cancer cells MCF-7 and MDA-MB-231 with IC50 of 0.12 and 0.25 uM, respectively.
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| DC11618 | KUNG38 |
A potent, selective Grp94 inhibitor with Kd of 0.44 uM.
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| DC11619 | KUNG29 |
A potent, selective Grp94 inhibitor with Kd of 0.2 uM.
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| DC11616 | KUNG94 |
A potent, selective Grp94 inhibitor with IC50 of 8 nM.
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| DC11921 | Bimoclomol |
A potent heat shock protein coinducer.
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| DC12011 | KU-32 |
A novel, novobiocin-based, C-terminal inhibitor of Hsp90 and a potent inducer of Hsp70.
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