ISO-92 is a potent inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity with IC50 of 0.55 uM..

ISO-66 is a novel, highly stable, small-molecule MIF inhibitor that inhibits MIF tautomerase activity with IC50 of 1.4 uM.

Isavuconazonium is a water-soluble prodrug form of the azole antifungal isavuconazole (ISA).

Isavuconazole(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557, exhibits MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata.

Isatoribine is a selective agonist of TLR7

Isatin is an endogenous MAO inhibitor.

ISA27 is a novel small molecule that blocks p53-MDM2 interaction and induces apoptosis both in vitro and in vivo.

ISA-2011B is a PIP5Kα inhibitor with promising anticancer effects .

IS-741 (Fuzapladib, IS741) is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2)..

IRE1α-IN-3 is a novel, potent IRE1α RNase inhibitor with EC50 of 0.82 uM.

Irdabisant (CEP-26401) is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity.

Irdabisant (CEP-26401) is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity.

Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels.

Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels.

IRAK inhibitor 6 is interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor .

IRAK inhibitor 2 is interleukin-1 receptor associated kinase inhibitor .

IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression, reverses the inhibitory effect of HBx protein on activity of the Dicer endoribonuclease.

IQM-266 (IQM266) is a DREAM (Downstream Regulatory Element Antagonist Modulator) ligand (Kd=4.63 uM), inhibits the KV4.3/DREAM current in a concentration-, voltage-, and time-dependent-manner.

Ipidacrine hydrochloride is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels.

Ipidacrine hydrochloride hydrate is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels.

IPI-9119 (IPI9119) is a potent, selective, and irreversible inhibitor of fatty acid synthase (FASN) with IC50 of 0.3 nM in biochemical assays.

IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).

iOWH032 is a novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays.

Iopamidol is a nonionic, low-osmolar iodinated contrast agent.

Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus.

Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus, used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes.

Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging.

INX-08189 is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay.

Interferon receptor agonist is an interferonm (IFN) receptor agonist.

Insulin levels modulator could be used to treat diabetes.