A-943931 is a potent, selective antagonist of histamine H4 receptor (H4R) with binding pKi of 8.33 and 8.42 for hH4 and rH4, respectively.

A-943931 dihydrochloride is a potent, selective antagonist of histamine H4 receptor (H4R) with binding pKi of 8.33 and 8.42 for hH4 and rH4, respectively.

A-867744 is a positive allosteric modulator of α7 nAChRs (IC50 values are 0.98 and 1.12 μM for human and rat α7 receptor ACh-evoked currents respectively, in X.

A-836339 (A836339) is a potent and selective cannabinoid CB2 receptor agonist with Ki of 0.64 and 0.76 nM for human and rat CB2 receptors, displays 425- and 189-fold selectivity over CB1 receptor, respectively.

A-832234 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 19 nM..

A-790742 is a potent human immunodeficiency virus type 1 (HIV-1) protease inhibitor, with 50% effective concentrations ranging from 2 to 7 nM against wild-type HIV-1.

A-740003 is potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively).

A-68930 is a potent, specific, orally bioavailable agonist of the D1 Dopamine receptor with EC50 of 2.5 nM.

A-484954 is a highly selective eukaryotic elongationfactor-2 (eEF2) inhibitor, with an IC50 of 280 nM.

A-395N is the negative control compound of A-395, which is a potent, selective, and cellularly active PRC2 subunit EED inhibitor with Kd of 1.5 nM..

A-357300 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 0.12 uM, does not inhibit MetAP1 or leucine aminopeptidases at 10 uM.

A-317567 (A317567) is a novel potent acid sensing ion channel (ASIC) blocker with IC50 of 2-30 uM.

A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.

A12B4C3 (hPNKP inhibitor A12B4C3) is a specific, noncompetitive inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase (hPNKP) with C50 of 60 nM, displays no inhibition of calcineurin and protein phosphatase-1 or APTX.

A-1048400(A 1048400) is a novel potent, selective, orally active N-type and T-type calcium channel blocker with IC50 of 1.4 and 1.2 uM, respectively.

A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo.

A widely used general anesthetic to induce and maintain anesthesia.

A water-soluble prodrug of triptolide that is highly effective in reducing pancreatic tumor growth and spread, and improving survival.

A water-soluble derivative of 17-AAG and HSP90 inhibitor.

A viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator.

A VHL ligand for PROTAC..

A VHL ligand for PROTAC..

A veterinary anthelmintic with known proton ionophore activities.

A veterinary anthelmintic with known proton ionophore activities.

A tyrphostin AG17 analog that exihibits potent Src-K inhibitory activity with IC50 of 2.2 uM.

A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors..

A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors..

A tritium-labeled allosteric modulator of the human chemokine receptor CXCR3 with Kd of 1.08 nM.

A triterpenoid compound that potently and selectively inhibits JAK/STAT3 pathway, suppresses the levels of phosphotyrosine STAT3 in A549 cell with IC50 of 500 nM.

A triple monoamine reuptake inhibitor, inhibits the reuptake of 5-HT, norepinephrine and dopamine in HEK 293 cells with IC50 of 12, 23 and 96 nM, respectively.