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Cat. No. Product Name Field of Application Chemical Structure
DC71875 Milpocitide
Milpocitide is a low-density lipoprotein receptor (human LDL receptor, LDLR), (293-333)-peptide fragment (EGF-like domain 1).
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DC71873 Mem-C1C18
Mem-C1C18 is a polarity-sensitive fluorescent probe with excellent plasma membrane anchoring, high brightness and a sensitive response to environmental polarity by altering the fluorescence lifetime. Mem-C1C18 can be used to quantify changes in the polarity of the plasma membrane during iron death.
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DC71872 Melitracen
Melitracen is an orally active tricyclic antidepressant and it is also a bipolar thymoleptic with activating properties. Melitracen inhibits 3H-5-HT and 14H-5-HT with IC50s of 670 nM and 5500 nM, respectively. Melitracen can be used for the research of depression and anxiety.
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DC71871 l-Naproxen
l-Naproxen ((R)-Naproxen) is an enantiomer of (S)-Naproxen. l-Naproxen can inhibit Cdc42 and Rac1 (EC50=96 μM and 212 μM, respectively), and show anti-tumor activity.
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DC71870 Leteprinim potassium
Leteprinim potassium (AIT-082) is a hypoxanthine derivative neurotrophic agent. Leteprinim potassium can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim potassium reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim potassium increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species. Leteprinim potassium has neuroprotective activity.
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DC71869 Kobusine derivative-2
Kobusine derivative-2, a kobusine derivative, has antiproliferative activity against cancer cells. Kobusine derivative-2 can induce the arrest of MDA-MB-231 cells in the sub-G1 phase. Anticancer activity.
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DC71868 Kobusine derivative-1
Kobusine derivative-1 is a Kobusine derivative. Kobusine derivative-1 shows antiproliferative activities against cancer cells.
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DC71867 JNJ-1289
JNJ-1289 is a potent, selective, competitive and allosteric human spermine oxidase (hSMOX) inhibitor (IC50: 50 nM). JNJ-1289 can be used in the research of polyamine catabolism, inflammation and cancers.
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DC71866 IR-990
IR-990 is an activatable NIR-II fluorescent probe with an acceptor-π-acceptor (A-π-A) skeleton for real-time detection of H2O2 in vivo. IR-990 is a powerful diagnosis of drug-induced liver injury (DILI).
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DC71865 Imbotolimod
Imbotolimod (trastuzumab imbotolimod), immunoglobulin G1-kappa, is a humanized monoclonal antibody with anti-ERBB2 and antineoplastic activity. Imbotolimod (trastuzumab imbotolimod) is a derivative of telratolimod .
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DC71864 Hydrocortisone phosphate sodium
Hydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) is a soft steroid with low anti-inflammatory properties and a short duration of action. Hydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) can be used for the research for several ocular conditions and gastric ulcers.
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DC71863 HITCI
HITCI is a commercially available, positively charged, indocarbocyanine dye used typically as a laser dye in the near infrared (NIR) .
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DC71862 HG-7-85-01-NH2
HG-7-85-01-NH2 is the ligand of SNIPER(ABL)-033. SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 value of 0.3 μM.
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DC71861 Gd-NMC-3
Gd-NMC-3 is a near-infrared fluorescence/magnetic resonance (NIRF/MR) bimodal imaging probe. Gd-NMC-3 shows high resolution and sensitivity in tumor imaging with good biocompatibility, indicating huge application potential.
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DC71860 FLDP-8
FLDP-8 is a curcuminoid analogues, has potent anti-cancer effects. FLDP-8 can induce cell death with an IC50 value of 4 μM in LN-18 cells.
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DC71859 FEMA 4774
FEMA 4774 is a positive allosteric modulator of taste receptors T1R2 and T1R3, two subunits of the human sweet taste receptor. FEMA 4774 is also used as a sucrose sweetness enhancer.
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DC71858 Ex26
Ex26 (S1P1-IN-Ex26) is a potent and selective Sphingosine 1-phosphate receptor 1 (S1P1) antagonist (IC50=0.93 nM). Ex26 shows >3,000-fold selectivity for S1P1 over other Sphingosine 1-phosphate receptors. Ex26 can be used in experimental autoimmune encephalomyelitis reseach.
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DC71857 Euphoscopin C
Euphoscopin C is a diterpenoid found in Euphorbia helioscopia. Euphoscopin C can significantly enhance the killing activity of NK cells against H1299 -luci cells and A549-luci cells.
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DC71856 Etedesiran
Etedesiran is a Myotonin-protein kinase (MT-PK, MDPK, or DMPK) inhibitor.
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DC71855 Epirosmanol
Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity.
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DC71854 DMT-5Me-dC(Bz)-CE Phosphoramidite
DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding.
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DC71853 DM-Nitrophen tertasodium
DM-Nitrophen tertasodium is a Ca2+ cage. DM-Nitrophen releases Ca2+ when cleaved upon illumination with near-ultraviolet light. DM-Nitrophen tertasodium can be used for study of Ca2+ signaling.
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DC71852 DM-Nitrophen
DM-Nitrophen is a Ca2+ cage. DM-Nitrophen releases Ca2+ when cleaved upon illumination with near-ultraviolet light.
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DC71851 DIBAC-GGFG-NH2CH2-Dxd
DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin derivative, is a linker-payload of protein-drug conjugates.
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DC71850 DB772 hydrate
DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity.
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DC71849 Colestilan
Colestilan (MCI-196) is a non-absorbed, non-calcium-based phosphate binder and is also a non-metallic, anion exchange resin. Colestilan is orally active and can be used for hypercholesterolaemia research.
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DC71848 Cedazuridine hydrochloride
Cedazuridine (E7727) (Compound 7a) hydrochloride is an orally active cytidine deaminase (CDA) inhibitor with an IC50 value of 0.4 μM. Cedazuridine hydrochloride can be used for cancer research.
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DC71846 Bocconoline
Bocconoline is a potent early endosome antigen 1 (EEA1) inhibitor. Bocconoline can be isolated from Macleaya cordata. Bocconoline can be used for the research of Parkinson’s disease (PD).
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DC71845 Berberine ursodeoxycholate
Berberine ursodeoxycholate (HTD1801), an ionic salt of Berberine and Ursodeoxycholic acid, is an orally active and potent hypolipidemic agent. Berberine ursodeoxycholate shows significantly great reduction in liver fat content. Berberine ursodeoxycholate has a broad spectrum of metabolic activity. Berberine ursodeoxycholate can be used for the research of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes.
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DC71844 Belatacept
Belatacept (BMS 224818) is a selective T-cell costimulation blocker. Belatacept binds to CD 80/86 ligands and thereby inhibits the CD-28-mediated T-cell costimulation. Belatacept can be used in the research of Immunosuppression in organ transplants.
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