Oxythiamin diphosphate ammonium is a potent transketolase (TK) inhibitor.

SLK/STK10-IN-1 is a potent and selective inhibitor of SLK and STK10 with nanomolar potency.

SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM.

Sinbaglustat (OGT2378) is a dual inhibitor of glucosylceramide synthase (GCS) and non-lysosomal glucosyl ceramidase (GBA2). Sinbaglustat is an orally available N-alkyl iminosugar that crosses the blood-brain barrier. Sinbaglustat can be used for the research of central neurodegenerative diseases associated with lysosomal dysfunctions.

R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. R-(+)-Cotinine can enhance the Ach-evoked current in human α7 nAChRs.

Peptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints of rheumatoid arthritis (RA).

TIM-3-IN-1 represents useful tool to further study the biology of TIM-3 immune modulation in cancer.

PREP inhibitor-1 is a highly potent prolyl oligopeptidase (PREP) inhibitor (IC50 < 1 nM).

MEIS-IN-3 is a potent myeloid ecotropic viral integration site (MEIS) inhibitor.

PDGFP 1 is a promising probe for simultaneously differentiating glioma boundary and grades.

Piceid 6″-O-azelaic acid ester shows high intracellular tyrosinase inhibitory and depigmentating activities.

MEIS-IN-1 is a potent myeloid ecotropic viral integration site (MEIS) inhibitor to induce murine and human hematopoietic stem-cell expansion.

Kdn probe-1 is a fluorescent Kdn probe and reveals the localization of AfS in vesicles at the cell surface.

MEIS-IN-2 is a myeloid ecotropic viral integration site 1 (MEIS1) inhibitor.

MtDTBS-IN-1 is a particularly potent binder (KD = 57 nM) and inhibitor (Ki = 5 μM) of MtDTBS.

Quorum Sensing-IN-1 is a small-molecule quorum sensing inhibitor.

Transketolase-IN-1 is a promising herbicide candidate for weed control in wheat and maize fields targeting transketolase.

LtIA-F, a novel fluorescent analogue of LtIA, provides a wealth of pharmacological tools to explore the structure–function relationship, distribution, and ligand binding domain of the α3β2 nAChR subtype.

Nitro-coronene can be used to prepare near-infrared light-triggered lysosome-targetable carbon dots for photothermal therapy of cancer.

RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).

NCATS-SM4487 is a highly selective unique dihydropyrimidine inhibitor against GALK1, with an IC50 value of 0.05 μM.

NCATS- SM4487 is a highly selective unique dihydropyrimidine inhibitor against GALK1, with an IC50 value of 0.05 μM.

NI-Pano (CH-03) is a novel hypoxia-activated KDAC inhibitor. NI-Pano (CH-03) is reduced in an O2-dependent manner to release panobinostat.

PPO-IN-1 is a potent protoporphyrinogen IX oxidase (PPO) inhibitor with a Ki value of 2.5 nM.

Lynamicin B is a potential pesticide by acting as a lepidoptera-exclusive chitinase inhibitor with a Ki value of 8.76 μM.

ThrRS-IN-2 is a threonyl-tRNA synthetase (ThrRS) inhibitor with an IC50 value of 56.5 ± 3.5 μM.

N-Octylmaleimide is an alkylmaleimide, which can inhibit rat liver glucose 6-phosphatase.

Salpyran is a Cu(II) selective chelator with therapeutic potential.

PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.

Plasma kallikrein-IN-1 is a PKK inhibitor with an IC50 value of 0.5 nM.