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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC48618 Amino-PEG6-acetic acid
Amino-PEG6-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48617 Sodium tetradecyl sulfate
Sodium tetradecyl sulfate (Tergitol 4) is a sclerosing agent used for the research of varicose veins.
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DC48616 Tetradecyl sulfate sodium
Tetradecyl sulfate sodium, a detergent sclerosant, is widely used agent for esophageal varices and varicose veins.
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DC48615 Iodo-PEG7-alcohol
Iodo-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48614 Pentetic acid
Pentetic acid is a compound used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater.
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DC48613 Palitantin
Palitantin ((±)-Palitantin), a metabolite of Penicillium frequentans on Leishmania brasiliensis, has antiprotozoal effect against Leishmania brasiliensis.
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DC48612 Isoamyl 4-(dimethylamino)benzoate
Isoamyl 4-(dimethylamino)benzoate can be used for the synthesis of inclusion complex (isoamyl4-(Dimethylamino)benzoate with sulfobutylether-β-cyclodextrin).
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DC48611 (R)-Preclamol
(R)-Preclamol is a dopamine (DA) agonist with autoreceptor as well as postsynaptic receptor stimulatory properties. (R)-Preclamol inhibits the locomotor activity of mice and rats in low doses.
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DC48610 Clonostachydiol
Clonostachydiol is an anthelmintic macrodiolide from the fungus Clonostachys cylindrospora (strain FH-A 6607).
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DC48609 Asperaculane B
Asperaculane B is a fungal metabolite against P. falciparum transmission with an IC50 of 7.89 µM. Asperaculane B also inhibits the development of asexual P. falciparum with IC50 of 3 µM, and it is nontoxic to human cells.
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DC48608 Aculene D
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations.
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DC48607 Cbz-PEG2-bromide
Cbz-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC48606 UCSF686
UCSF686 is a probe with which to study the function of the 5-HT5AR. UCSF686 loses affinity at 5-HT5AR (>10 000 nM) but not at 5-HT1AR, 5-HT2BR, and 5-HT7R. UCSF686 controls for off-target effects.
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DC48605 Sulfo-NHS-Biotin sodium
Sulfo-NHS-Biotin (sodium) stongly label single SDS-2ME soluble cuticular protein.
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DC48604 Cefetamet
Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections.
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DC48603 Chaetosemin J
Chaetosemin J, an antifungal metabolite, exhibits inhibitory activity against plant pathogenic fungi Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, with MIC values ranging from 12.5-25 μM.
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DC48602 Ticlopidine
Ticlopidine (PCR 5332), an antithrombotic prodrug, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 µM. Ticlopidine blocks several NTPDase isoenzymes with IC50s of 170 µM and 149 µM for NTPDase2 and NTPDase3, respectively. Ticlopidine is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine inhibits CYP2C9 and CYP3A4 with IC50s of 26.0 and 32.3 μM, respectively.
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DC48601 Clopirac
Clopirac is a potent and orally active inhibitor of prostaglandin synthetase. Clopirac is an anti-inflammatory agent.
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DC48600 2-Methoxyphenyl benzoate
2-Methoxyphenyl benzoate is an active compound.
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DC48599 CK7
CK7, a Cdk2/9 inhibitor, can be used for the synthesis of Nek1 inhibitor BSc5231 and BSc5367.
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DC48598 FTO-IN-6
FTO-IN-6 is a selective fat mass and obesity associated protein (FTO) inhibitor.
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DC48597 BTA-1
BTA-1 is an uncharged derivative of thioflavin-T. BTA-1 has high affinity for Aβ fibrils and shows very good brain entry and clearance.
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DC48596 Pulixin
Pulixin prevents FREP1 from binding to P. falciparum-infected cell lysate. Pulixin blocks the transmission of the parasite to mosquitoes with an EC50 of 11 µM. Pulixin also inhibits the proliferation of asexual-stage P. falciparum with an EC50 of 47 nM.
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DC48595 Resveratrol-3-O-sulfate sodium
Resveratrol-3-O-sulfate (sodium) is the metabolite of Resveratrol.
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DC48594 Oosporein
Oosporein is a red crystalline metabolite produced by a toxin-producing strain of Chaetomium trilaterale. Chaetomium trilaterale is isolated from moldy Peanuts. Oosporein inhibits plant growth and produces phytotoxic effects.
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DC48593 Norfunalenone
Norfunalenone exhibits weak cytotoxic activity in mouse myeloma NS-1 cell line (ATCC TIB-18) with an IC50 of 70 μM. Norfunalenone also exhibits weak antibacterial activity against B. subtilis (MIC=100 μg/mL; IC50=265 μM).
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DC48592 Indolokine A5
Indolokine A5, a catabolite of L-cysteine, is a potent AhR agonist.
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DC48591 Octamylamine
Octamylamine is an anticholinergic and antispasmodic agent.
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DC48590 Cholera autoinducer 1
Cholera autoinducer 1 is Vibrio cholerae autoinducer (S)-3-hydroxytridecan-4-one. Cholera autoinducer 1 influences chemotaxis in C. elegans.
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DC48589 Epsilon-(gamma-glutamyl)-lysine TFA
Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration.
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