Novel capsid targeted inhibitor of HIV-1 replication

Novel GluN2B subtype-selective NMDA antagonist

Human flap endonuclease 1 (FEN1) inhibitor

Novel agonist of insect olfactory receptors (ORs) acting at a binding site on the Orco subunit

Literature References: Exists as a glucoside in the rhizomes of Podophyllum peltatum L., Berberidaceae: von Wartburg et al.,Helv. Chim. Acta 40, 1331 (1957). Isoln from resin podophyllum: Hartwell, Detty, J. Am. Chem. Soc. 70, 2833 (1948); 72, 246 (1950);