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Cat. No. Product Name Field of Application Chemical Structure
DC36339 Dansyl chloride
Dansyl chloride is a reactive probe for the derivatization of primary amines, including those on amino acids, peptides, and polyamines, for detection by HPLC. It has also been used for the derivatization of compounds containing phenol groups, such as steroids, for detection by MS/MS. Dansyl chloride is a fluorescent probe for proteins and enzymes. It displays excitation/emission maxima of 340/535 nm, respectively, in acetone.
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DC36326 Rebaudioside D
Rebaudioside D is a natural non-caloric sweetener. It is a steviol glycoside metabolized by gut microbiota to steviol, a compound whose safety is widely studied.
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DC36318 NSC-207895
NSC-207895 is an inhibitor of the p53-binding protein MDMX. NSC 207895 decreases the expression and protein levels of MDMX and increases the expression of the p53 target gene CDKN1 (p21). It also increases the expression of the pro-apoptotic genes PUMA, Bax, and PIG3. NSC 207895 induces apoptosis and decreases cell viability in MCF-7 cells in a p53-dependent manner. It also induces p53-independent apoptosis in wild-type, mutated, and truncated p53 Ewing sarcoma cell lines selectively over wild-type and p53-null osteosarcoma cells
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DC36287 Alaproclate HCl
Alaproclate HCl is a selective serotonin reuptake inhibitor (SSRI). It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum. Alaproclate inhibits NMDA-evoked currents and depolarization-induced voltage-dependent potassium currents in rat hippocampal neurons.
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DC36272 (-)-ε-Viniferin
trans-ε-Viniferin is a stilbene polyphenol and dimer of trans-resveratrol that has been found in various red wines. It induces disaggregation of aggregated amyloid-β (1-42) (Aβ42) fibrils and decreases Aβ42- and IL-1β-induced release of TNF-α and IL-6 in primary mouse neuron and astrocyte cocultures. trans-ε-Viniferin reduces cytotoxicity induced by truncated huntingtin (Htt) in PC12 cells. It also reduces production of reactive oxygen species (ROS), mitochondrial dysfunction, and PGC-1α depletion and increases protein levels and deacetylase activity of sirtuin 3 (SIRT3) in cells expressing mutant Htt. trans-ε-Viniferin inhibits calcium-activated chloride channel currents in HT-29 cells. In vivo, trans-ε-viniferin reduces rotavirus-induced secretory diarrhea in mice without affecting the rotaviral infection. Dietary administration of trans-ε-viniferin reduces hepatic triglyceride accumulation and body weight increases in a mouse model of diet-induced obesity.
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DC36229 Aminomethyltrioxsalen hydrochloride
Aminomethyltrioxsalen hydrochloride is a psoralen compound DNA intercalator used to inactivate DNA and RNA viruses, including HIV-1, by nucleic acid cross-linking followed by UV irradiation.
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DC36211 Amiridine
Ipidacrine is a ring-constricted derivative of tacrine (Cognex) and a reversible acetylcholinesterase inhibitor used in memory disorders. Ipidacrine directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.
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DC36189 Algestone
Algestone is a synthetic progestational dihydroxy derivative of Progesterone. The acetonide group possesses anti-inflammatory properties.
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DC36173 Alergosan
Chloropyramine hydrochloride may be useful in the treatment of invasive breast cancer.
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DC36162 AI3-52151
Tyramine hydrochloride is an indirect sympathomimetic. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and monoamine oxidase, so it prolongs the actions of adrenergic transmitters. It also provokes transmitter release from adrenergic terminals. Tyramine may be a neurotransmitter in some invertebrate nervous systems.
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DC36150 AI3-62629
Ibacitabine is an antiviral drug.
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DC36143 AI3-63120
Zoxazolamine is a uricosuric and muscle relaxant of which the mechanism of action is not well understood.
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DC36141 Aivlosin
Tylvalosin is an antibacterial drug.
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DC36109 Abbocillin
Penicillin G procaine is a semisynthetic antibiotic prepared by combining penicillin G with Procaine.
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DC36105 Adrenalone hydrochloride
Adrenone hydrochloride displays antineoplastic activity and has been shown to inhibit growth of Ehrlich ascites tumors in mice.
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DC36068 Arecoline
Arecoline is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice.
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DC36051 Anatabine
Anatabine is one of the minor alkaloids found in plants in the Solanaceae family, which includes the tobacco plant and tomato. Anatabine may be useful for treating nicotine addiction and inflammation, Alzheimer's Disease, thyroiditis, and multiple sclerosis.
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DC36023 SPDP-PEG4-acid
SPDP-PEG4-acid is a PEG Linker.
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DC35718 Azido-PEG4-t-butyl ester
Azido-PEG4-t-butyl ester is a PEG derivative containing an azide group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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DC35616 diethyl 4-bromobutylphosphonate
diethyl 4-bromobutylphosphonate
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DC35611 Tetraethyl decane-1
Tetraethyl decane-1,10-diylbis(phosphonate) is a non-PEG crosslinker.
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DC35610 Tetraethyl octane-1,8-diylbis(phosphonate)
Tetraethyl octane-1,8-diylbis(phosphonate) is a non-PEG crosslinker.
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DC35609 Tetraethyl heptane-1
Tetraethyl heptane-1,7-diylbis(phosphonate) is a non-PEG Crosslinker.
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DC35578 m-PEG3-Ms
m-PEG3-Ms is a PEG derivative containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35577 m-PEG11-Tos
m-PEG11-Tos is a PEG derivative containing a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35571 m-PEG5-Tos
m-PEG5-Tos is a PEG derivative containing a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35570 m-PEG4-Tos
m-PEG4-Tos is a PEG derivative containing a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35554 m-PEG4-azide
m-PEG4-azide is a PEG derivative containing an azide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35535 m-PEG4-NHS ester
m-PEG4-NHS ester is a PEG derivative containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35506 NH-bis(PEG4-OH)
NH-bis(PEG4-OH) is a branched PEG derivative with a central amino group and two terminal hydroxyl groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls, etc. The hydroxy groups enable further derivatization or replacement with other reactive functional groups.
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