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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC32580 MYCi975 Featured
MYCi975, also known as NUCC-0200975, is a potent and selective MYC Inhibitor. MYCi975 disrupts MYC/MAX interaction, promotes MYC T58 phosphorylation and MYC degradation, and impairs MYC driven gene expression.
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DC32374 Nicotinamide Mononucleotide Featured
Nicotinamide Mononucleotide, also known as ("NMN" and "β-NMN") is a nucleotide derived from ribose and nicotinamide Like nicotinamide riboside, NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinuc
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DC26175 NLX-101(F-15599) Featured
NLX-101(F-15599) is a novel compound that activates serotonin 5-HT1A receptors with exceptional selectivity, having over 1000-fold higher affinity for this target over other receptors.
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DC7221 P22077 Featured
P22077 is a potent inhibitor of ubiquitin-specific protease (USP) 7 (EC50=8.6 uM), P22077 also inhibits the closely related deubiquitinase (DUB) USP47.
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DC5188 Sarecycline(P005672 hydrochloride) Featured
P005672 is a phase II drug for antibacterial/anti-inflammatory acne treatment.
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DC7222 P005091(P5091) Featured
P005091(P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM.
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DC12312 OTX008 (Calixarene 0118; PTX008) Featured
OTX008 is a selective inhibitor of galectin-1.
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DC5195 Omecamtiv mecarbil (CK-1827452) Featured
Omecamtivmecarbil (CK-1827452) is a specific cardiac myosinactivator and a clinical drug for left ventricular systolic heart failure.
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DC10473 NVS-PAK1-1 Featured
NVS-PAK1-1 potently inhibits autophosphorylation of PAK1 (S144) at 0.25 µM in the Su86.86 cell line and MEK S289 phosphorylation with an IC50 = 0.21 in Su86.86 cells in which PAK2 is downregulated.
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DC9769 NVP-CGM097 (CGM-097) Featured
NVP-CGM097 (CGM-097) is a potent and selective MDM2 inhibitor.
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DC26035 NUC-7738 Featured
NUC-7738 is a phosphoramidate transformation of cordycepin (3’-deoxyadenosine; 3’-dA), a derivative of adenosine that was first isolated from Cordyceps sinensis.
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DC5047 NU7026 Featured
NU7026 is a potent DNA-PK inhibitor with IC50 of 0.23 μM, 60-fold selective for DNA-PK than PI3K and inactive against both ATM and ATR.
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DC7165 NSI-189 Featured
NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.
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DC10484 NSC781406 Featured
NSC781406 is a highly potent PI3K and mTOR inhibitor with an IC50 of 2 nM for PI3Kα.
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DC20228 NSC617145(WRN inhibitor) Featured
NSC617145 is a Werner syndrome helicase (WRN) helicase inhibitor (IC50 = 250 nM).
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DC9641 NSC348884 Featured
NSC348884 is a nucleolar phosphoprotein that displays several biological activities in ribosome biogenesis, cell proliferation, cytoplasmic/nuclear shuttle transportation, nucleic acid binding, ribonucleic cleavage, and centrosome duplication.
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DC8783 NS 9283 Featured
NS 9283 is a positive allosteric modulator of α4β2 receptor; increases the potency of Ach-evoked currents ~60 fold without effecting the maximum efficacy (HEK293-hα4β2 cells).
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DC8398 NPS-1034 Featured
NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.
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DC4111 Nolatrexed (AG-337) Featured
Nolatrexed (AG-337), inhibits purified recombinant human thymidylate synthase (TS) with a Ki of 11 nM, and displays non-competitive inhibition kinetics. It was further shown to inhibit cell growth in a panel of cell lines of murine and human origin, displ
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DC7212 NMS-873 Featured
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 20 nM (Wild Type, 1 mM ATP).
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DC5172 NLG919(GDC-0919) Featured
NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM.
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DC9786 NKP-1339 Featured
NKP-1339 is the first-in-class ruthenium-based anticancer drug in clinical development against solid cancer and has recently been studied successfully in a phase I clinical trial.
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DC9561 Nitisinone Featured
Nitisinone(SC0735) is an inhibitor of the enzyme 4-hydroxyphenylpyruvate dioxygenase.
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DC10028 NIH-12848 Featured
NIH-12848 (NCGC00012848-02) is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor, was explored as a tool for investigating this enigmatic, low activity,
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DC7977 Nicaraven Featured
Nicaraven is an antivasospastic substance.
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DC8076 NG 52 (Compound 52 ) Featured
NG 52 (Compound 52) is a potent, cell-permeable, reversible, selective, and ATP-compatible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC50 = 7 μM), and the related Pho85p kinase (IC50 = 2 μM).
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DCAPI1393 Nedaplatin (Aqupla) Featured
Nedaplatin (Aqupla) is a derivative of cisplatin for inhibition of tumor colony forming units with IC50 of 28.5 μg/mL.
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DC2084 Necrostatin-1 Featured
Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM.
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DC10438 N-Desmethylclozapine Featured
N-Desmethylclozapine is a dengue virus inhibitor, and an agonist of δ-opioid receptor.
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DC9810 ND-646 Featured
ND-646(ND646) is a small-molecule allosteric inhibitor of acetyl-CoA carboxylase (ACC).
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