NCGC00063279 is a novel inhibitor of the werner syndrome helicase-nuclease (wrn) helicase

6-PNG is a Cav3.2 (T-type) calcium channel blocker.

Rifamycin is a natural antibiotic which inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis, thereby blocking RNA-polymerase transcription initiation.

Micheliolide is a natural, irreversible activator of pyruvate kinase M2, and a suppressor of leukemia cells.

TD-3 is an inhibitor of the salt-bridge formation between β-Asp94 and β-His146 hemoglobin (Hb), binding to Hb β-Cys93.

Halofuginone Hydrobromide is a potent prolyl-tRNA synthetase inhibitor.

NSC-57969 is a MDR-selective agent, exhibiting a robust Pgp-dependent toxic activity across diverse cancer cell lines.

Enbucrilate is a tissue adhesive, forming polymer films at oil-water interfaces and revealing films of diverse morphology.

Toltrazuril (Tol) is a broad-spectrum anticoccidiosis drug that is widely used in the prevention and treatment of coccidiosis infection in poultry and mammals.

HDAC8-IN-2 is a selective HDAC8 inhibitor.

Cilostamide is a selective inhibitor of type III phosphodiesterase (PDE3).

(±)-Blebbistatin is a cell cycle inhibitor and a selective inhibitor of non-muscle myosin II.

MeBIO is a negative control analog of BIO, and an aryl hydrocarbon receptor (AhR) agonist. It causes redistribution of AhR to the nucleus.

Paroxetine maleate is a selective serotonin reuptake inhibitor and an antidepressant.

DTNB is an allosteric inhibitor of the NS2B-NS3 protease from dengue virus. It acts as a reagent for the determination of reactive sulfhydryl groups.

RO8191 is an activator of JAK/STAT that induces IFN-like signals.

TSI-01 is a selective inhibitor of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2 (LPCAT2).

AQ4 is a topoisomerase II inhibitor and DNA intercalator.

Buserelin Acetate is a Gonadotropin-releasing hormone agonist (GnRH agonist).

Amodiaquin dihydrochloride is an inhibitor of the Ebola virus. It acts by targeting the viral protein 35 (VP35).

BSBM7 is an inhibitor of Aβ aggregation and neuronal toxicity. It acts by reversing the aggregation and toxicity of amyloid-β (Aβ) peptides.

Moxalactam Disodium is a broad- spectrum beta-lactam antibiotic.

MS21570 is a GPR171 antagonist that reduces anxiety-like behavior and fear conditioning in mice.

Gly-Pro-Arg-Pro Acetate is an inhibitor of fibrinogen aggregation that acts by binding to fibrinopeptide A.

Acyclovir sodium is an antimetabolite. It inhibits HSV-specified DNA polymerases and prevents further viral DNA synthesis without affecting the normal cellular processes.

17A-Hydroxyprogesterone is a metabolite of progesterone. It serves as an intermediate in the biosynthesis of hydrocortisone and gonadal steroid hormones.

Isosorbide is a precursor of Isosorbide mononitrate or dinitrate, which relax vascular smooth muscle by formation of the free radical nitric oxide (NO).

Oe-9000 is a novel blocker of voltage-gated Na(+) currents in neurons. It reversibly reduces slowly activating and inactivating tetrodotoxin-resistant (TTX-R) Na(+) currents as well as rapidly activating and inactivating TTX-sensitive (TTX-S) Na(+) currents at low micromolar concentrations.

MDK-4025 is an inhibitor of the high voltage-activated (HVA) Ca2+ current in pyramidal neurons. The last four digits of the compound's CAS registry number are used in its name.

Lisofylline, also known as LSF, improves cellular mitochondrial function and blocks interleukin-12 (IL-12) signaling and STAT-4 activation in target cells and tissues. IL-12 and STAT-4 activation are important pathways linked to inflammation and autoimmune damage to insulin producing cells. Therefore, LSF and related analogs could provide a new therapeutic approach to prevent or reverse type 1 diabetes.