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Cat. No. Product Name Field of Application Chemical Structure
DC36170 Albadry
Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity.
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DC36368 Antibiotic PF 1052
Antibiotic PF 1052 is a fungal metabolite active against S. aureus, S. parvulus, and C. perfringens. It inhibits neutrophil migration, reduces pseudopodia formation, and induces rounding of neutrophils. Antibiotic PF 1052 is selective for neutrophil migration over macrophage migration in zebrafish larvae. It also inhibits the migration of murine neutrophils.
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DC34305 KT185
KT185 is the first orally-active ABHD6-selective inhibitor. It displays excellent selectivity against other brain and liver serine hydrolases in vivo.
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DC36570 Cloransulam-methyl
Cloransulam-methyl is a herbicide.
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DC36521 Pigment Blue 15
Pigment Blue 15, also called by many names (EINECS 205-685-1), is a bright, crystalline, synthetic blue pigment from the group of phthalocyanine dyes. Its brilliant blue is frequently used in paints and dyes. It is highly valued for its superior properties such as light fastness, tinting strength, covering power and resistance to the effects of alkalis and acids. It has the appearance of a blue powder, insoluble in water and most solvents.
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DC37071 AI 3-09536
AI 3-09536 is a biochemical.
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DC37729 L-6424
L-6424 is an intermediate of Amiodarone, a non-selective ion channel blocker and an antiarrhythmic.
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DC34252 Oxolinic acid
Oxolinic acid is an inhibitor of DNA-gyrase (topoisomerase II). It acts by inhibiting dopamine reuptake.
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DC34287 Adenosine N1-oxide
Adenosine N1-oxide is an inhibitor of secretion of inflammatory mediators. It acts by suppressing pro-inflammatory cytokine secretion.
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DC37430 Xanthosine
Xanthosine treatment has been demonstrated to promote expansion of putative mammary stem cells. Xanthosine treatment also increased the proliferation rate of bovine MEC in vitro
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DC33848 BODIPY FL Ester
BDP FL NHS ester is an advanced dye for 488 nm channel, a replacement for fluorescein, a molecule identical to BODIPY FL? NHS ester. An amino-reactive dye for the labeling of proteins and peptides. The dye is neutral, possesses low molecular weight, and retains high quantum yield in conjugates. The dye is a good replacement for fluorescein (FAM), BODIPY-FL, Alexa Fluor 488, DyLight 488, Cy2, and other 488 nm dyes.
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DC34667 Fluphenazine hydrochloride
Fluphenazine is a antipsychotic medication. It is used in the treatment of chronic psychoses such as schizophrenia. Fluphenazine exerts its actions by blocking postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia. This prevents the actions of dopamine, thereby reducing the hallucinations and delusions that are associated with schizophrenia. It is given by mouth, injection into a muscle, or just under the skin.
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DC35820 Mal-PEG3-alcohol
Mal-PEG3-alcohol is a PEG derivative containing a maleimide group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC34565 NSC345308
WR-1065 Dihydrochloride is a metabolite of Amifostine.
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DC35473 THP-PEG6
THP-PEG6 is a PEG derivative. PEG derivatives may be useful in the development of antibody drug conjugates.
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DC34550 Sulfo-Cy5-acid
CY5 is a photoswitchable fluorescent labeling reagent.
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DC36252 5-Methyluridine
5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine. It enhances the antitumor activity of 5-fluorouracil in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.
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DC34840 Propargyl-PEG17-methane
Propargyl-PEG17-methane is a PEG derivative containing a propargyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC37660 Selegiline
Selegiline is a selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.
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DC37872 Tris(benzyloxycarbonyl)arginine
NSC-120011, also known as Tris(benzyloxycarbonyl)arginine, is a bioactive chemical.
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DC33717 Ketopioglitazone
Ketopioglitazone is an active metabolite of pioglitazone and is found in human plasma.
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DC36813 Leriglitazone
Leriglitazone is a peroxisome proliferator activated receptor (PPAR) gamma agonist.
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DC36838 Chlorindanol
Chlorindanol is a spermaticide.
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DC35951 Propargyl-PEG2-Tos
Propargyl-PEG2-Tos is a PEG derivative containing a tosyl group and a propargyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
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DC35086 Biotin-PEG4-alkyne
Biotin-PEG4-alkyne is a PEG derivative containing a biotin group and an alkyne group. The alkyne group can react with azide moiety in Cu(I)-catalyzed Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.
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DC34056 Sophoridine hydrate
Sophoridine is an antiviral against Coxsackievirus B3. Sophoridine works by regulating cytokine expression which may represent a potential therapeutic agent for viral myocarditis. Sophoridine also has anti-tumor and anti-inflammatory properties.
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DC35467 m-PEG4-(CH2)3-alcohol
m-PEG4-(CH2)3-alcohol is a PEG derivative containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35365 Fluorescein-PEG4-azide
Fluorescein-PEG4-azide is a heterofunctional fluorescent PEG derivative containing an azide group, which enables Click Chemistry. The hydrophilic PEG spacer arm increases solubility in aqueous media. The FITC group (Fluorescein) can be easily traced from its yellow color and green fluorescence.
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DC34505 MNF
MNF, also known as 3,4-MNF, is an antagonist of the aryl hydrocarbon receptor (AhR). MNF reduces UVR-mediated immunosuppression and induces Tregs in murine contact hypersensitivity (CHS).
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DC35947 Tos-PEG4-acid
Tos-PEG4-acid is a PEG derivative containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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