Novel Inhibitor of the Disordered Protein, p27(Kip1)

Novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate(NMDA) receptor antagonist

The first potent biased small molecule agonist at the apelin receptor, increasing cardiac contractility in vivo

Potent inhibitor of SUV420H1 (IC50 = 25 nM) and SUV420H2 (IC50 = 144 nM), a closely related pair of proteins which catalyze the di- and tri-methylation of H4K20

Novel potent inhibitor of the lysophospholipase autotaxin

Selective group I mGlu receptor agonist

Bioavailable metabolite of the prodrug GW5638 as an antiestrogen thought to promote degradation of Er?

An inducer for Cell Apoptosis Through JNK and ERK1/2 Signaling Pathways in Colon Cancer Cells