AI 3-09536 is a biochemical.

L-6424 is an intermediate of Amiodarone, a non-selective ion channel blocker and an antiarrhythmic.

Oxolinic acid is an inhibitor of DNA-gyrase (topoisomerase II). It acts by inhibiting dopamine reuptake.

Adenosine N1-oxide is an inhibitor of secretion of inflammatory mediators. It acts by suppressing pro-inflammatory cytokine secretion.

Xanthosine treatment has been demonstrated to promote expansion of putative mammary stem cells. Xanthosine treatment also increased the proliferation rate of bovine MEC in vitro

BDP FL NHS ester is an advanced dye for 488 nm channel, a replacement for fluorescein, a molecule identical to BODIPY FL? NHS ester. An amino-reactive dye for the labeling of proteins and peptides. The dye is neutral, possesses low molecular weight, and retains high quantum yield in conjugates. The dye is a good replacement for fluorescein (FAM), BODIPY-FL, Alexa Fluor 488, DyLight 488, Cy2, and other 488 nm dyes.

Fluphenazine is a antipsychotic medication. It is used in the treatment of chronic psychoses such as schizophrenia. Fluphenazine exerts its actions by blocking postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia. This prevents the actions of dopamine, thereby reducing the hallucinations and delusions that are associated with schizophrenia. It is given by mouth, injection into a muscle, or just under the skin.

Mal-PEG3-alcohol is a PEG derivative containing a maleimide group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

WR-1065 Dihydrochloride is a metabolite of Amifostine.

THP-PEG6 is a PEG derivative. PEG derivatives may be useful in the development of antibody drug conjugates.

CY5 is a photoswitchable fluorescent labeling reagent.

5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine. It enhances the antitumor activity of 5-fluorouracil in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.

Propargyl-PEG17-methane is a PEG derivative containing a propargyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.

Selegiline is a selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.

NSC-120011, also known as Tris(benzyloxycarbonyl)arginine, is a bioactive chemical.

Ketopioglitazone is an active metabolite of pioglitazone and is found in human plasma.

Leriglitazone is a peroxisome proliferator activated receptor (PPAR) gamma agonist.

Chlorindanol is a spermaticide.

Propargyl-PEG2-Tos is a PEG derivative containing a tosyl group and a propargyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Biotin-PEG4-alkyne is a PEG derivative containing a biotin group and an alkyne group. The alkyne group can react with azide moiety in Cu(I)-catalyzed Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

Sophoridine is an antiviral against Coxsackievirus B3. Sophoridine works by regulating cytokine expression which may represent a potential therapeutic agent for viral myocarditis. Sophoridine also has anti-tumor and anti-inflammatory properties.

m-PEG4-(CH2)3-alcohol is a PEG derivative containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.

Fluorescein-PEG4-azide is a heterofunctional fluorescent PEG derivative containing an azide group, which enables Click Chemistry. The hydrophilic PEG spacer arm increases solubility in aqueous media. The FITC group (Fluorescein) can be easily traced from its yellow color and green fluorescence.

MNF, also known as 3,4-MNF, is an antagonist of the aryl hydrocarbon receptor (AhR). MNF reduces UVR-mediated immunosuppression and induces Tregs in murine contact hypersensitivity (CHS).

Tos-PEG4-acid is a PEG derivative containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

TC-E 5002 is a selective histone demethylase KDM2/7 subfamily inhibitor.

cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone. It is also a potential impurity found in commercial preparations of entacapone and a degradant of entacapone formed by UV light exposure.

GHRP-6 acetate is a synthetic growth hormone (GH) secretagogue and an agonist of the GH secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It inhibits binding of the GHS-R agonist MK-0677 (Ibutamoren) to COS-7 cell membranes expressing human GHS-R type Ia and binding of ghrelin to COS-7 cells expressing human GHS-R. GHRP-6 stimulates intracellular calcium mobilization in BHK cells expressing the human receptor and inositol phosphate production in COS-7 cells expressing the human receptor. It also acts as a negative allosteric modulator of ghrelin signaling. GHRP-6 induces release of GH, but not thyroid-stimulating hormone (TSH), luteinizing hormone (LH), or follicle-stimulating hormone (FSH), in isolated rat pituitary gland. It increases levels of GH, but not TSH, LH, FSH, or prolactin, in rat blood when administered subcutaneously at a dose of 50 μg. GHRP-6 increases food intake in rats when administered intracerebroventricularly at 0.3, 1, and 3 nmol.

allo-DL-Threonine is a racemic mixture of the D and L isomers of the polar essential amino acid threonine.

Cyanine5.5 dye, free acid form, unactivated. The dye can be considered non-reactive for most applications. It can be used as a control or reference sample, and for instrument calibration.