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PI3K/Akt/mTOR

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Cat. No. Product Name Field of Application Chemical Structure
DC11841 LAS191954
A potent, selective, orally bioavailable PI3Kδ inhibitor with IC50 of 2.6 nM.
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DC11656 AMPK-Activator-13
A potent, allosteric, α1-selective small molecule activator of AMPK (EC50=20 nM).
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DC11938 IPI-3063
A novel, potent, and selective p110δ PI3K inhibitor with IC50 of 0.1 nM in cell-based assays.
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DC11795 BL-140
A novel specific p110β inhibitor with IC50 of 5.74 nM.
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DC11631 INCB040093
A novel potent, selective, orally available PI3Kδ inhibitor with IC50 of 31 nM.
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DC11599 PF-739
A novel potent, pan-AMPK activator with similar potency for all AMPK heterotrimers.
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DC11968 OSU-03013
A novel potent, orally active 3-phosphoinositide-dependent kinase-1 (PDK-1) with IC50 of 2 uM.
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