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PROTACs

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Cat. No. Product Name Field of Application Chemical Structure
DC44031 Benzyl-PEG2-CH2COOH
Benzyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44028 m-PEG1000-CH2COOH
m-PEG1000-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44027 NH2-PEG-Strt (MW 3000)
NH2-PEG-Strt (MW 3000) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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DC44026 NH2-PEG-Strt (MW 10000)
NH2-PEG-Strt (MW 10000) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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DC44025 m-PEG750-Br
m-PEG750-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44024 Boc-NH-PEG-Thiol (MW 10000)
Boc-NH-PEG-Thiol (MW 10000) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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DC44022 Hydroxy-PEG4-methyl acetate
Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44016 Benzyl-PEG2-acid
Benzyl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44014 H2N-PEG2-CH2COOtBu
H2N-PEG2-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44011 Propenyl-PEG3-Propenyl
Propenyl-PEG3-Propenyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44010 BOC-NH-PEG2-propene
BOC-NH-PEG2-propene is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC43972 Thalidomide-NH-C2-PEG3-OH
Thalidomide-NH-C2-PEG3-OH is an E3 ligase ligand-linker conjugate that incorporates Thalidomide based cereblon ligand and a linker used for PROTAC BCL-XL degrader XZ739.
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DC43971 Thalidomide-NH-PEG4-Ms
Thalidomide-NH-PEG4-Ms is an E3 ligase ligand-linker conjugate that incorporates Thalidomide based cereblon ligand and a linker used for PROTAC BCL-XL degrader XZ739.
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DC22337 E3 ligase Ligand 4(TC-E3 5032) Featured
E3 ligase Ligand 4 is a ligand of E3 ligase, used in PROTAC technology.
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DC42435 LC-2 Featured
LC-2 is a potent and first-in-class degrader of endogenous KRAS G12C with DC50 values between 0.25 and 0.76 μM. LC-2 covalently binds KRAS G12C with a MRTX849 warhead and recruits the E3 ligase VHL, inducing rapid and sustained KRAS G12C degradation leading to suppression of MAPK signaling in both homozygous and heterozygous KRAS G12C cell lines.
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DC42555 (S,R,S)-AHPC-PEG5-Boc
(S,R,S)-AHPC-PEG5-Boc is a E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for Cdc20 degrader CP5V.
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DC42554 Pomalidomide 4'-PEG5-acid
Pomalidomide 4'-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology.
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DC42238 Chlorobutanol hemihydrate
Thalidomide 5-fluoride is Thalidomide-based cereblon ligand?that incorporates to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
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DC42235 Monoethyl itaconate
NH2-PEG1-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC42230 m-PEG7-thiol
m-PEG7-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC42099 Maleimide-C10-NHS ester
Maleimide-C10-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC41140 Amino-PEG4-C1-Boc
Amino-PEG4-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC41058 Biotin-PEG4-hydrazide TFA
Biotin-PEG4-hydrazide (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC41057 L-Azidohomoalanine hydrochloride
L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC41056 N-(Amino-PEG2)-N-bis(PEG3-azide)
N-(Amino-PEG2)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC41045 Pomalidomide-PEG1-C2-COOH
Pomalidomide-PEG1-C2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology.
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DC41044 PROTAC KRASG12C Degrader-LC-2
PROTAC KRASG12C Degrader-LC-2 is a potent and first-in-class degrader of endogenous KRAS G12C with DC50 values between 0.25 and 0.76 μM. PROTAC KRASG12C Degrader-LC-2 is composed of a covalent KRAS G12C inhibitor MRTX849, a VHL ligand and a linker.
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DC40887 Thiol-PEG-Tetrazine (MW 5kDa)
Thiol-PEG-Tetrazine (MW 5kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40867 Boc-A 410099.1 amide-alkylC4-amine
Boc-A 410099.1 amide-alkylC4-amine is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-alkylC4 linker with terminal amine. Boc-A 410099.1 amide-alkylC4-amine can conjugates with target protein ligands.
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DC40866 A 410099.1 amide-PEG2-amine-Boc
A 410099.1 amide-PEG2-amine-Boc is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-PEG3 linker with terminal amine. A 410099.1 amide-PEG2-amine-Boc can conjugates with target protein ligands.
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