AZD-3988

Cas No.:	892489-52-0
Chemical Name:	trans-4-[-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid
Synonyms:	AZD-3988, AZD3988, AZD 3988
SMILES:	C1CC(CCC1CC(=O)O)C2=CC=C(C=C2)NC(=O)C3=NN=C(O3)NC4=CC(=C(C=C4)F)F
Formula:	C23H22F2N4O4
M.Wt:	456.44
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Potent and selective diacylglycerol acyltransferase (DGAT-1) inhibitor (IC50 = 0.6 nM). Exhibits selectivity for DGAT-1 over DGAT-2, Kv11.1 (hERG) and cytochrome P450 enzymes. Suppresses triacylglyceride (TAG) plasma excursion and adipose tissue TAG synthesis in rats. Reduces body weight of diet-induced obese rats. Cell permeable and orally bioavailable. For the detailed information of AZD-3988, the solubility of AZD-3988 in water, the solubility of AZD-3988 in DMSO, the solubility of AZD-3988 in PBS buffer, the animal experiment (test) of AZD-3988, the cell expriment (test) of AZD-3988, the in vivo, in vitro and clinical trial test of AZD-3988, the EC50, IC50,and affinity,of AZD-3988, For the detailed information of AZD-3988, the solubility of AZD-3988 in water, the solubility of AZD-3988 in DMSO, the solubility of AZD-3988 in PBS buffer, the animal experiment (test) of AZD-3988, the cell expriment (test) of AZD-3988, the in vivo, in vitro and clinical trial test of AZD-3988, the EC50, IC50,and affinity,of AZD-3988, Please contact DC Chemicals.