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| Cas No.: | 1801343-74-7 |
| Chemical Name: | N-(1-(6'-amino-[2,3'-bipyridin]-5-yl)vinyl)-2-morpholinooxazolo[4,5-c]pyridin-6-amine |
| Synonyms: | CA-4948; CA 4948; CA4948 |
| SMILES: | O=C(C1=CC=CC(C2=CC=C(N)N=C2)=N1)NC3=CN=C4C(OC(N5CCOCC5)=N4)=C3 |
| Formula: | C21H19N7O3 |
| M.Wt: | 417.42 |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | CA-4948 is a selective and potent IRAK4 inhibitor. |
| In Vivo: | CA-4948 is a selective and potent IRAK4 inhibitor which can be used as a therapeutic agent for hematological cancers with dysregulated TLR/MYD88/IRAK4 signaling. CA-4948 exhibits favorable DMPK properties, oral bioavailability, and is well tolerated in mice. Furthermore, CA-4948 is previously shown to exhibit dose-dependent efficacy in ABC-DLBCL MYD88-L265P xenograft tumor models[1]. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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| 2018-0101 |
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