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DC10SMe

  Cat. No.:  DC28766  
Chemical Structure
For research use only. We do not sell to patients.
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More than 5000 active chemicals with high quality for research!
Field of application
DC10SMe is a DNA alkylator, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC10SMe exhibits IC50s of 15 pM, 12 pM, and 12 pM for Ramos, Namalwa, and HL60/s cancer cells, respectively.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.:
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC47126 Corixetan Corixetan is a highly efficient thorium chelator. Corixetan can efficiently complex Th-227 with sufficient in vivo stability.
DC46937 Seco-DUBA Seco-DUBA is a duocarmycin (DUBA) prodrug containing two hydroxyl groups, which can each be used for coupling to an antibody via a linker. Seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs).
DC46260 DMEA-PNU-159682 DMEA-PNU-159682 (molecule D12) is a ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682.
DC46252 Azonafide-PEABA Azonafide-PEABA is a cytotoxic drug moiety.
DC46215 Tubulysin IM-1 Tubulysin IM-1 is an ADC Cytotoxin and tubulin binder used as anti-microtubule toxins.
DC45523 Seco-DUBA hydrochloride Seco-DUBA hydrochloride is a toxin for ADC drug SYD985.
DC44785 7-MAD-MDCPT 7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs).
DC44784 MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), a camptothecin payload, can be conjugated to a monoclonal antibody (mAb) for the synthesis of camptothecin antibody-drug conjugate (ADC).
DC41129 Sandramycin Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity.
DC40469 Muscotoxin A Muscotoxin A is an?ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death.
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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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