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Seco-DUBA hydrochloride

  Cat. No.:  DC45523  
Chemical Structure
1795733-93-5
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More than 5000 active chemicals with high quality for research!
Field of application
Seco-DUBA hydrochloride is a toxin for ADC drug SYD985.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1795733-93-5
Chemical Name: Seco-DUBA hydrochloride
SMILES: ClC[C@H]1C2=C(C=C(C3=CC=CC(C)=C32)O)N(C1)C(C4=CN(C=C(C=C5)NC(C6=CC=C(C=C6)O)=O)C5=N4)=O.Cl[H].[x]
Formula: C29H23ClN4O4.XClH
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_29246_DC45523_1795733-93-5
COA
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Cat. No. Product name Field of application
DC47126 Corixetan Corixetan is a highly efficient thorium chelator. Corixetan can efficiently complex Th-227 with sufficient in vivo stability.
DC46937 Seco-DUBA Seco-DUBA is a duocarmycin (DUBA) prodrug containing two hydroxyl groups, which can each be used for coupling to an antibody via a linker. Seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs).
DC46260 DMEA-PNU-159682 DMEA-PNU-159682 (molecule D12) is a ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682.
DC46252 Azonafide-PEABA Azonafide-PEABA is a cytotoxic drug moiety.
DC46215 Tubulysin IM-1 Tubulysin IM-1 is an ADC Cytotoxin and tubulin binder used as anti-microtubule toxins.
DC45523 Seco-DUBA hydrochloride Seco-DUBA hydrochloride is a toxin for ADC drug SYD985.
DC44785 7-MAD-MDCPT 7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs).
DC44784 MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), a camptothecin payload, can be conjugated to a monoclonal antibody (mAb) for the synthesis of camptothecin antibody-drug conjugate (ADC).
DC41129 Sandramycin Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity.
DC40469 Muscotoxin A Muscotoxin A is an?ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death.
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