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STING CDN agonist IFM Therapeutics

  Cat. No.:  DC11179  
Chemical Structure
2197188-04-6
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More than 5000 active chemicals with high quality for research!
Field of application
STING CDN agonist IFM Therapeutics is a synthetic cyclic dinucleotide (CDN) agonist of STING, stimulates potent immunity against cancer..
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2197188-04-6
Chemical Name: (2R,3R,3aS,7aR,9R,10R,10aS,14aR)-2,9-bis(6-amino-9H-purin-9-yl)-3,10-dihydroxydodecahydrodifuro[3,2-d:3',2'-j][1,3,7,9]tetraazacyclododecine-5,12(4H,6H)-dione
SMILES: N1C[C@@]([H])2O[C@H](N3C4C(N=C3)=C(N)N=CN=4)[C@@H](O)[C@@]2([H])NC(=O)NC[C@@]([H])2O[C@H](N3C4C(N=C3)=C(N)N=CN=4)[C@@H](O)[C@@]2([H])NC1=O
Formula: C22H26N14O6
M.Wt: 582.542
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: STING CDN agonist IFM Therapeutics is a synthetic cyclic dinucleotide (CDN) agonist of STING, stimulates potent immunity against cancer.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC47180 IACS-8803 diammonium IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 diammonium has a robust systemic antitumor efficacy.
DC47134 Cyclic-di-GMP diammonium Cyclic di-GMP (c-di-GMP) diammonium is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species.
DC46506 E7766 disodium E7766 disodium is a macrocycle-bridged STING agonist with a Kd of 40 nM. E7766 disodium shows potent pan-genotypic and antitumor activities.
DC46412 STING agonist-3 trihydrochloride STING agonist-3 trihydrochloride, extracted from patent WO2017175147A1 (example 10), is a selective and non-nucleotide small-molecule STING agonist with a pEC50 and pEC50 of 7.5 and 9.5, respectively. STING agonist-3 trihydrochloride has durable anti-tumor effect and tremendous potential to improve treatment of cancer.
DC45896 E7766 diammonium salt E7766 diammonium salt is a macrocycle-bridged STING agonist with a Kd of 40 nM. E7766 diammonium salt shows potent pan-genotypic and antitumor activities.
DC44158 IACS-8803 disodium IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy.
DC40210 STING ligand-1 STING ligand-1 is a lead STING ligand with an IC50 of 68 nM for HAQ STING.
DC40090 Cyclic-di-GMP sodium Cyclic di-GMP sodium (c-di-GMP sodium) is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species.
DC11179 STING CDN agonist IFM Therapeutics STING CDN agonist IFM Therapeutics is a synthetic cyclic dinucleotide (CDN) agonist of STING, stimulates potent immunity against cancer..
DC11072 SINCRO SINCRO is a novel anti-cancer compound that can activate the cytosolic DNA-sensing STING signaling pathway leading to the induction of type I interferon (IFN) genes.
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