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| Cas No.: | 1423018-12-5 |
| Chemical Name: | (S)-3-(4-((5-((8-methoxy-3,4-dihydroquinolin-1(2H)-yl)methyl)thiophen-2-yl)methoxy)phenyl)hex-4-ynoic acid |
| Synonyms: | LY-2922470;LY 2922470 |
| SMILES: | C(O)(=O)C[C@H](C1=CC=C(OCC2SC(CN3C4=C(C=CC=C4OC)CCC3)=CC=2)C=C1)C#CC |
| Formula: | C28H29NO4S |
| M.Wt: | 475.603 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | LY2922470 (LY-2922470) is a potent, selective, orally available GPR40 agonist with EC50 of 7 nM; displays no activity against PPARα/β/γ (>10 uM); demonstrates potent, efficacious, and durable dose-dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion in vivo. |