Cas No.: | 1853130-05-8 |
Chemical Name: | N-(5-(((4',5'-difluoro-2'-(methylthio)-[1,1'-biphenyl]-4-yl)oxy)methyl)furan-2-carbonyl)-N-(furan-2-ylmethyl)glycinate |
Synonyms: | AJS-1669;AJS 1669 |
SMILES: | C(O)(=O)CN(C(C1=CC=C(COC2=CC=C(C3=CC(F)=C(F)C=C3SC)C=C2)O1)=O)CC1=CC=CO1 |
Formula: | C26H20F2NO6S |
M.Wt: | 512.504 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A novel potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM; shows no activity for GYS2; improves glucose metabolism and reduces body fat mass in mice. |