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| Cas No.: | 1374524-68-1 |
| Chemical Name: | 2H-1-Benzopyran-7-ol, 3,4-dihydro-3,4-bis(4-hydroxyphenyl)-8-methyl-, (3R,4S)- |
| Synonyms: | 843G0TDV51;(3R,4S)-3,4-bis(4-hydroxyphenyl)-8-methyl-3,4-dihydro-2H-chromen-7-ol;4,4'-(7-Hydroxy-8-methylchroman-3,4-diyl)diphenol;GTPL7961;DB13062;2H-1-Benzopyran-7-ol, 3,4-dihydro-3,4-bis(4-hydroxyphenyl)-8-methyl-, (3R,4S)-;Q27083823;4,4'-((3R,4S)-7-Hydroxy-8-methylchroman-3,4-diyl)diphenol;GLXC-15476;ME 344 [WHO-DD];DTXSID701031261;1374524-68-1;CHEMBL5314386;SCHEMBL10073998;UNII-843G0TDV51;CS-0063310;mTOR1/2 Kinase Inhibitor ME-344;(3R,4S)-3,4-bis(4-hydroxyphenyl)-8-methyl-3,4-dihydro-2H-1-benzopyran-7-ol;Me 344;HY-112749;NS00073416;ME-344 |
| SMILES: | O1C2C(C)=C(C=CC=2[C@H](C2C=CC(=CC=2)O)[C@H](C2C=CC(=CC=2)O)C1)O |
| Formula: | C22H20O4 |
| M.Wt: | 348.391806602478 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM; inhibits oxygen consumption rates, with specific effects on the respiratory chain, causes complex, redox-specific, and mitochondria-targeted effects in lung cancer cells; reduces tumor growth in OCI-AML2 xenograft model; an active metabolite of NV-128. |