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BWA-522 intermediate-1

  Cat. No.:  DC67726   Featured
Chemical Structure
2241315-66-0
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Field of application
BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 (HY-149433) and serves as a ligand molecule for cereblon E3 ubiquitin ligase. BWA-522 is an orally active small molecule protein-targeting chimera (PROTAC) that has significant degradation effects on AR-FL and AR-V7.
Cas No.: 2241315-66-0
Chemical Name: BWA-522 intermediate-1
Synonyms: BWA-522 INTERMEDIATE-1;1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-4-Piperidinecarboxaldehyde;1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidine-4-carbaldehyde;G76763;SCHEMBL20317461;2241315-66-0;DB-421292
SMILES: O=C1C2C=C(C=CC=2C(N1C1C(NC(CC1)=O)=O)=O)N1CCC(C=O)CC1
Formula: C19H19N3O5
M.Wt: 369.371264696121
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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