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CRBN ligand-877

  Cat. No.:  DC67827   Featured
Chemical Structure
2244684-41-9
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More than 5000 active chemicals with high quality for research!
Field of application
CRBN ligand-877 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.
Cas No.: 2244684-41-9
Chemical Name: (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
Synonyms: AT11466;(2S,4R)-1-((S)-2-AMINO-3,3-DIMETHYLBUTANOYL)-4-HYDROXY-N-(2-HYDROXY-4-(4-METHYLTHIAZOL-5-YL)BENZYL)PYRROLIDINE-2-CARBOXAMIDE HCL;(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
SMILES: Cl.S1C=NC(C)=C1C1C=CC(=C(C=1)O)CNC([C@@H]1C[C@H](CN1C([C@H](C(C)(C)C)N)=O)O)=O
Formula: C22H31ClN4O4S
M.Wt: 483.02
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC67845 N-Me-Thalidomide 4-fluoride N-Me-Thalidomide 4-fluoride is a ligand for E3 ligase, used for the synthesis of Anti-inflammatory agent 70 .
DC67844 CRBN ligand-880 CRBN ligand-880 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-880 can be linked to a target protein ligand via a linker to form a PROTAC.
DC67843 6-hydroxy-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
DC67842 Tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperazine-1-carboxylate
DC67841 Boc-NH-PEG4 Boc-NH-PEG4 (PROTAC Linker 12) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
DC67840 tert-Butyl (6-hydroxyhexyl)carbamate tert-Butyl (6-hydroxyhexyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
DC67839 tert-Butyl N-(2,6-dioxopiperidin-3-yl)carbamate (Standard) tert-Butyl N-(2,6-dioxopiperidin-3-yl)carbamate (Standard) is the analytical standard of tert-Butyl N-(2,6-dioxopiperidin-3-yl)carbamate. This product is intended for research and analytical applications.
DC67838 3-amino-1-methylpiperidine-2,6-dione hydrochloride
DC67837 (S)-3-Amino-piperidine-2,6-dione hydrochloride
DC67836 (R)-3-Aminopyrrolidine-2,5-dione (R)-3-Aminopyrrolidine-2,5-dione is a potential anticonvulsant agent and its derivatives have comparable in vivo efficacy.
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