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| Cas No.: | 1352608-82-2 |
| Chemical Name: | Vactosertib |
| Synonyms: | EW 7197;1H-Imidazole-2-methanamine, N-(2-fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-;EW-7197;N-(2-Fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo-[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine;Vactosertib;TEW-7197;N-(2-Fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine;N-[[4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1h-imidazol-2-yl]methyl]-2-fluoroaniline;GTPL8107;C22H18FN7;6T4O391P5Y;EX-A1 |
| SMILES: | FC1=C([H])C([H])=C([H])C([H])=C1N([H])C([H])([H])C1=NC(C2C([H])=C([H])C3=NC([H])=NN3C=2[H])=C(C2=C([H])C([H])=C([H])C(C([H])([H])[H])=N2)N1[H] |
| Formula: | C22H18FN7 |
| M.Wt: | 399.42 |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Vactosertib (EW-7197) is an ATP-competitive inhibitor of ALK5 with an IC50 of 12.9 nM. It also inhibits ALK2 and ALK4 at nanomolar concentrations. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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