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GNE-490

  Cat. No.:  DC8502   Featured
Chemical Structure
1033739-92-2
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More than 5000 active chemicals with high quality for research!
Field of application
GNE-490 is a highly selective pan-PI3K inhibitor and demonstrates selectivity over mTOR.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1033739-92-2
Chemical Name: 2-[6-(2-amino-4-methylpyrimidin-5-yl)-1-morpholin-4-yl-2,4-dihydrothieno[3,2-d]pyrimidin-3-yl]propan-2-ol
Synonyms: GNE490;GNE 490
SMILES: CC1=NC(=NC=C1C2=NC3=C(C(=N2)N4CCOCC4)SC(=C3)C(C)(C)O)N
Formula: C18H22N6O2S
M.Wt: 386.5
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: GNE-490 is a highly selective pan-PI3K inhibitor and demonstrates selectivity over mTOR.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
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DC42415 IHMT-PI3Kδ-372 IHMT-PI3Kδ-372 is a potent and selective PI3Kδ with an IC50 of 14 nM. IHMT-PI3Kδ-372 shows high selectivity over other class I PI3Ks (56∼83 fold) and other protein kinases. IHMT-PI3Kδ-372 can be uesd for chronic obstructive pulmonary disease (COPD) research.
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DC40777 MSC2360844(IOA-244 /roginolisib) MSC2360844 is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. MSC2360844 shows highly selective against a panel of 278 additional kinases.
DC28978 Copanlisib dihydrochloride (BAY 80-6946) Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively. Copanlisib dihydrochloride has
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