JH-X-119-01 hydrochloride|CAS 0|DC Chemicals

Cas No.:
Chemical Name:	JH-X-119-01 hydrochloride
SMILES:	O=C(C=C)NC1=CC=CC(C(NC2=CC=C(NC(C3=NC(C4=CC=NN4)=CC=C3)=O)C=C2)=O)=C1.Cl
Formula:	C₂₅H₂₁ClN₆O₃
M.Wt:	488.93
Sotrage:	Powder-20°C3 years4°C2 years In solvent-80°C6 months-20°C1 month

Cat. No.	Product name	Field of application
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DC40577	IRAK inhibitor 4	IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4(IRAK4) inhibitor.
DC40037	JH-X-119-01 hydrochloride	JH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in mice.
DC28331	IRAK4-IN-4	IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.
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