JNJ-28312141|cas 885692-52-4|DC Chemicals|Price|Buy

Cas No.:	885692-52-4
Chemical Name:	4-cyano-N-(5-(1-(2-(dimethylamino)acetyl)piperidin-4-yl)-2',3',4',5'-tetrahydro-[1,1'-biphenyl]-2-yl)-1H-imidazole-2-carboxamide
Synonyms:	JNJ-28312141; JNJ28312141; JNJ 28312141.
SMILES:	O=C(C1=NC(C#N)=CN1)NC2=C(C3=CCCCC3)C=C(C4CCN(C(CN(C)C)=O)CC4)C=C2
Formula:	C₂₆H₃₂N₆O₂
M.Wt:	460.57
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

JNJ-28312141 is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and also a FLT3 inhibitor. CSF1R is expressed by many tumors and is a growth factor For macrophages and mediates osteoclast differentiation. JNJ-28312141 represents a new agent with potential therapeutic activity in acute myeloid leukemia and in settings where CSF-1-dependent macrophages and osteoclasts contribute to tumor growth and skeletal events. For the detailed information of JNJ-28312141, the solubility of JNJ-28312141 in water, the solubility of JNJ-28312141 in DMSO, the solubility of JNJ-28312141 in PBS buffer, the animal experiment (test) of JNJ-28312141, the cell expriment (test) of JNJ-28312141, the in vivo, in vitro and clinical trial test of JNJ-28312141, the EC50, IC50,and Affinity of JNJ-28312141, Please contact DC Chemicals.

Cat. No.	Product name	Field of application
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