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Home > Inhibitors & Agonists > Epigenetics > Bromodomain

(+)-JQ1 carboxylic acid

  Cat. No.:  DC10656   Featured
Chemical Structure
202592-23-2
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Field of application
(+)-JQ1 carboxylic acid is the carboxylic acid form of (+)-JQ1 for derivative synthesis.
Chemicals PropertiesBiological activity Related products COA MSDS Datasheet
Cas No.: 202592-23-2
Chemical Name: JQ1-Carboxylic acid
Synonyms: 6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, (6s)-;(+)-JQ-1 carboxylic acid;JQ-1 carboxylic acid;2-((6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetic acid;LJOSBOOJFIRCSO-UHFFFAOYSA-N;(+/-)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid;[(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6Hthieno[3,2-f;JQ-1 (carboxylic acid)
SMILES: ClC1C([H])=C([H])C(=C([H])C=1[H])C1C2C(C([H])([H])[H])=C(C([H])([H])[H])SC=2N2C(C([H])([H])[H])=NN=C2C([H])(C([H])([H])C(=O)O[H])N=1
Formula: C19H17ClN4O2S
M.Wt: 400.88
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: JQ-1 carboxylic acid is a highly potent, selective and cell-permeable BRD4 inhibitor with IC50s of 77 nM and 33 nM for BRD4(1) and BRD4(2), respectively.
Cat. No. Product name Field of application
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