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PSMA-617 Linker

  Cat. No.:  DC33611   Featured
Chemical Structure
1703768-74-4
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More than 5000 active chemicals with high quality for research!
Field of application
Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is widely used in the treatment of metastatic castration-resistant prostate cancer (mCRPC) due to its ability to deliver targeted radiation directly to PSMA-expressing cancer cells, minimizing damage to surrounding healthy tissues.
Cas No.: 1703768-74-4
Chemical Name: Vipivotide tetraxetan Ligand-Linker Conjugate
Synonyms: PSMA-617 Linker;Vipivotide tetraxetan Linker;JUN68744;(((S)-5-((S)-2-((1r,4S)-4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanamido)-1-carboxypentyl)carbamoyl)-L-glutamic acid;Vipivotide tetraxetan Ligand-Linker Conjugate
SMILES: O=C(C1CCC(CN)CC1)N[C@H](C(NCCCC[C@@H](C(=O)O)NC(N[C@H](C(=O)O)CCC(=O)O)=O)=O)CC1C=CC2C=CC=CC=2C=1
Formula: C33H45N5O9
M.Wt: 655.738508939743
Purity: >98%
Sotrage: -20
Publication: [1]. Benešová M, et al. Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile. Mol Pharm. 2018 Mar 5;15(3):934-946.
Description: Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is composed of a linker and Glutamate-urea-Lysine, can be used to synthesize Vipivotide tetraxetan (PSMA-617). Glutamate-urea-Lysine is is the selective pharmacophore to bind to prostate specific membrane antigen (PSMA).
MSDS
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COA
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Cat. No. Product name Field of application
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