MCH(human, mouse, rat)|CAS 128315-56-0|DC Chemicals

Cas No.:	128315-56-0
Chemical Name:	MCH(human, mouse, rat)
Synonyms:	DFDMLRCMLGRVYRPCWQV (Disulfide bridge:Cys7-Cys16)
Formula:	C₁₀₅H₁₆₀N₃₀O₂₆S₄
M.Wt:	2386.84
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

Cat. No.	Product name	Field of application
DC44915	Ac-hMCH(6–16)-NH2	Ac-hMCH(6-16)-NH2 binds to and activates equally well both human MCH receptors present in the brain (non-selective agonist), with IC50 values of 0.16 nM and 2.7 nM for MCH-1R and MCH-2R.
DC41658	MCH(human, mouse, rat) TFA	MCH (human, mouse, rat) TFA is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9?nM and 0.1nM for human MCH-1R and MCH-2R, respectively.
DC41657	MCH(human, mouse, rat)	MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9?nM and 0.1nM for human MCH-1R and MCH-2R, respectively.
DC28203	TC-MCH 7c	TC-MCH 7c, a phenylpyridone derivative, is an orally available, selective and brain-penetrable MCH1R antagonist with an IC50 of 5.6 nM for hMCH1R. TC-MCH 7c has Kis of 3.4 nM and 3.0 nM of human and mouse MCH1R, respectively.