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Home > Inhibitors & Agonists > Proteasome/Ubiquitin > p97/VCP

ML-241

  Cat. No.:  DC9307   Featured
Chemical Structure
1346528-06-0
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More than 5000 active chemicals with high quality for research!
Field of application
ML241 is a potent, selective, and reversible inhibitor of the AAA ATPase p97 (IC50=100 nM). It blocks p97-dependent proteasome substrate with an IC50 of 3500 nM.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1346528-06-0
Chemical Name: ML241 free base
Synonyms: ML241，ML 241
SMILES: C1CCC2=C(C1)C(=NC(=N2)N3CCOC4=CC=CC=C43)NCC5=CC=CC=C5
Formula: C23H24N4O
M.Wt: 372.463
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: ML241 is a potent, selective, and reversible inhibitor of the AAA ATPase p97 (IC50=100 nM). It blocks p97-dependent proteasome substrate with an IC50 of 3500 nM.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC9307 ML-241 ML241 is a potent, selective, and reversible inhibitor of the AAA ATPase p97 (IC50=100 nM). It blocks p97-dependent proteasome substrate with an IC50 of 3500 nM.
DC8576 ML-240 ML-240 functions as a potent ATP-competitive inhibitor targeting the p97 ATPase, demonstrating inhibitory activity with an IC50 value of 110 nM.
DC8840 CB-5083 CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models .
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