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Mitochondrial respiration-IN-1 hydrobromide

  Cat. No.:  DC42343  
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
Mitochondrial respiration-IN-1 hydrobromide (compound 49) is a potent mitochondrial (IC50=8.8 mg/ml) extracted from patent US20110301180A1, compound 49. Mitochondrial respiration-IN-1 hydrobromide significantly reduces mitochondrial respiration in platelets.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.:
Chemical Name: Mitochondrial respiration-IN-1 hydrobromide
SMILES: O=C(OCCC1=C(C)N=CS1)C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[H]Br.[Br-]
Formula: C26H26Br2NO2PS
M.Wt: 607.34
Sotrage: -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
MSDS
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MSDS_25950_DC42343
COA
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Cat. No. Product name Field of application
DC42344 MPP+ iodide MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT).
DC42343 Mitochondrial respiration-IN-1 hydrobromide Mitochondrial respiration-IN-1 hydrobromide (compound 49) is a potent mitochondrial (IC50=8.8 mg/ml) extracted from patent US20110301180A1, compound 49. Mitochondrial respiration-IN-1 hydrobromide significantly reduces mitochondrial respiration in platelets.
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DC40416 HQNO HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species.
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