Onapristone|CAS 96346-61-1|DC Chemicals

Cas No.:	96346-61-1
Chemical Name:	Onapristone
Synonyms:	ZK-89299;ZK-299;AR-18;IVV-1001
SMILES:	C[C@]12[C@](CC[C@]2(O)CCCO)([H])[C@@]3([H])C([C@@H](C4=CC=C(N(C)C)C=C4)C1)=C5C(CC3)=CC(CC5)=O
Formula:	C₂₉H₃₉NO₃
M.Wt:	449.62
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

Cat. No.	Product name	Field of application
DC45892	Promegestone	Promegestone (R-5020), a progestin, is a potent progesterone receptor (PR) agonist. Promegestone has the potential for endocrine regulation and cancer research.
DC9605	Dienogest	Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis.
DC77029	Onapristone	Onapristone is a progesterone receptor antagonist, with Kds of 11.6 nM and 11.90 nM for human endometrium and myometrium progesterone receptor in saturation analysis. Onapristone has antitumor activity.
DC77028	11α-Hydroxytestosterone	11α-Hydroxytestosterone is a deriviative of Hydrocortisone, with the relative binding affinity to progesterone receptor of 9% (comparing to R5020119384) 100%). 11α-Hydroxytestosterone inhibits the growth and differentiation of human decidual cells in culture.
DC73853	AG-205	A small molecule inhibitor of progesterone receptor membrane component 1 (PGRMC1) that alters the spectroscopic properties of the PGRMC1-heme complex.
DC72233	Norgestrienone	Norgestrienone, progestin or synthetic progestin, is a progestin receptor agonist. Norgestrienone is often used as a progestational compound in birth control pills and can be used in combination with ethinyl estradiol.
DC71566	Dexamethasone oxetanone	Dexamethasone oxetanone (Dex-Ox), a derivative of the glucocorticoid-selective steroid Dexamethasone (Dex), is an antiglucocorticoid. Dexamethasone oxetanone is an antiprogestin with significant agonist activity with progesterone receptor (PR) A and B isoforms.
DC49828	Progesterone-13C2	Progesterone-13C2 (Pregn-4-ene-3,20-dione-13C2) is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.