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PHM-27 (human)

  Cat. No.:  DC41560  
Chemical Structure
118025-43-7
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Field of application
PHM-27 (human) is a human prepro-vasoactive intestinal polypeptide (27 amino acid). PHM-27 (human) is a potent the human calcitonin receptor agonist with an EC50 of 11 nM. PHM-27 (human) efficiently enhances glucose-induced insulin secretion from beta cells by an autocrine mechanism.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 118025-43-7
Chemical Name: PHM-27 (human)
Synonyms: HADGVFTSDFSKLLGQLSAKKYLESLM-NH2
Formula: C135H214N34O40S
M.Wt: 2985.41
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_24573_DC41560_118025-43-7
COA
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Cat. No. Product name Field of application
DC41881 Calcitonin (human) Calcitonin human is an endogenous calcitonin receptor agonist.Calcitonin human lowers systemic blood calcium levels and inhibits bone resorption.
DC41849 Adrenomedullin (16-31), human TFA Adrenomedullin (16-31), human TFA is amino acid residues 16-31 fragment of human adrenomedullin (hADM). Adrenomedullin has appreciable affinity for the CGRP1 receptor. Adrenomedullin (16-31), human TFA possesses pressor activity in the systemic vascular bed of the rat, but not the cat.
DC41560 PHM-27 (human) PHM-27 (human) is a human prepro-vasoactive intestinal polypeptide (27 amino acid). PHM-27 (human) is a potent the human calcitonin receptor agonist with an EC50 of 11 nM. PHM-27 (human) efficiently enhances glucose-induced insulin secretion from beta cells by an autocrine mechanism.
DC29116 Adrenomedullin (AM) (22-52), human TFA Adrenomedullin (AM) (22-52), human (22-52-Adrenomedullin human) TFA, an NH2 terminal truncated adrenomedullin analogue, is an adrenomedullin receptor antagonist. Adrenomedullin (AM) (22-52), human also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat.
DC10370 Olcegepant hydrochloride Olcegepant hydrochloride is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP.
DC9397 MK-3207 (Hydrochloride) MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC50= 0.12 nM; Ki value= 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3.
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