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| Cas No.: | 104632-26-0 |
| Chemical Name: | Pramipexole |
| Synonyms: | Pramipexole; Oprymea; Pramipexol; Pramipexolum; |
| SMILES: | CCCNC1CCC2N=C(SC=2C1)N |
| Formula: | C10H17N3S |
| M.Wt: | 211.327 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Pramipexole is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS).Pramipexole also possesses low/insignificant affinity (500-10,000 nM) for the 5-HT1A, 5-HT1B, 5-HT1D, and α2-adrenergic receptors. It has negligible affinity (>10,000 nM) for the D1, D5, 5-HT2, α1-adrenergic, β-adrenergic, H1, and mACh receptors. All sites assayed were done using human tissues. While pramipexole is used clinically, its D3-preferring receptor binding profile has made it a popular tool compound for preclinical research. Pramipexole has been used (in combination with D2- and or D3-preferring antagonists) to interrogate the role of D3 receptor function in rodent models and tasks for neuropsychiatric disorders. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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