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RB-394

  Cat. No.:  DC11430  
Chemical Structure
1830320-32-5
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More than 5000 active chemicals with high quality for research!
Field of application
RB394 is an orally bioavailable and dual modulator of soluble epoxide hydrolase (sEH) and PPARγ.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1830320-32-5
Chemical Name: 2-(4-((4-methoxy-2-(trifluoromethyl)benzyl)carbamoyl)benzyl)butanoic acid
Synonyms: RB394;RB 394
SMILES: C(C(F)(F)F)1=CC(OC)=CC=C1CNC(=O)C1=CC=C(CC(CC)C(=O)O)C=C1
Formula: C21H22F3NO4
M.Wt: 409.405
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC46879 (S)-Coriolic acid (S)-Coriolic acid (13(S)-HODE), the product of 15-lipoxygenase (15-LOX) metabolism of linoleic acid, functions as the endogenous ligand to activate PPARγ. (S)-Coriolic acid is an important intracellular signal agent and is involved in cell proliferation and differentiation in various biological systems. (S)-Coriolic acid induces mitochondrial dysfunction and airway epithelial injury.
DC46878 AMG131 AMG131 (INT131), a potent and highly selective PPARγ partial agonist, binds to PPARγ and displaces Rosiglitazone with a Ki of ~10 nM. AMG131 can be used for research of type-2 diabetes mellitus (T2DM).
DC45608 FK614 FK614 is an orally active, potent, selective PPARγ modulator (SPPARM). FK614 has different effects on the activation of PPARγ at each stage of adipocyte differentiation. FK614 is a nonthiazolidinedione insulin sensitizer. FK614 can be used for the research of hyperglycemia, hypertriglyceridemia, glucose intolerance and type 2 diabetes.
DC41468 Caulophyllogenin Caulophyllogenin is a triterpene saponin extracted from M. polimorpha. Caulophyllogenin is a partial PPARγ agonist, with an EC50?of?12.6?μM. Caulophyllogenin can be used for the research of type-2 diabetes, obesity, metabolic syndrome and inflammation.
DC41439 Methyl oleanonate Methyl oleanonate is a natural triterpene PPARγ agonist isolated from the species of Pistacia. Methyl oleanonate is a modified oleanolic acid derivative with anti-cancer effects.
DC40731 Ciprofibrate impurity A Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate (Win35833) is a potent peroxisome proliferator, increases the phosphorylation level of the PPARalpha.
DC40032 GSK376501A GSK376501A is a selective peroxisome proliferator-activated receptor gamma (PPARγ) modulator for the treatment of type 2 diabetes mellitus.
DC29028 LY518674 LY518674 is a potent, selective PPARα antagonist, with an EC50 of 42 nM for human PPARα. LY518674 reduces triglycerides in and increased HDL-C and is used for the treatment of atherosclerosis.
DC28684 iRucaparib-AP6 iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using the PROTAC approach. iRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1.
DC11430 RB-394 RB394 is an orally bioavailable and dual modulator of soluble epoxide hydrolase (sEH) and PPARγ.
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