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Home > Inhibitors & Agonists > GPCR > Dopamine Receptor

SKF 77434

  Cat. No.:  DC26135   Featured
Chemical Structure
300561-58-4
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More than 5000 active chemicals with high quality for research!
Field of application
Selective dopamine D1-like receptor partial agonist (IC50 values are 19.7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 300561-58-4
Synonyms: SKF 77434,SKF-77434,SKF77434
SMILES: Br.OC1=CC2=C(C=C1O)C(CN(CC=C)CC2)C1=CC=CC=C1
Formula: C19H21NO2.HBr
M.Wt: 376.29
Description: Selective dopamine D1-like receptor partial agonist (IC50 values are 19.7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC26135 SKF 77434 Selective dopamine D1-like receptor partial agonist (IC50 values are 19.7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.
DC12379 SKF 38393 SKF 38393 is a partial agonist of the dopamine D1-like receptors D1 and D5 (Kis = 1 and ~0.5 nM, respectively).
DC10189 SCH 23390 hydrochloride SCH 23390 hydrochloride is a potent dopamine receptor D1 antagonist with Ki values of 0.2 and 0.3 nM for the D1 and D5.
DC6911 pardoprunox (SLV308) Pardoprunox(SLV-308) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist; D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist (IA = 50% and 67%, respectively) and 5-HT1A receptor (pKi = 8.5) full agonist (IA
DC9675 Pardoprunox.HCl(SLV-308) Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.
DC8286 Brexpiprazole(OPC34712) Brexpiprazole is a novel D2 dopamine partial agonist.
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