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| Cas No.: | 2018300-62-2 |
| Synonyms: | TPOP-146; TPOP 146 |
| SMILES: | COC1=CC(OC)=CC(C2=CC(C(N[C@H]3CCCN(C)C3)=O)=C(OCCN(C(CC)=O)C4)C4=C2)=C1 |
| Formula: | C27H35N3O5 |
| M.Wt: | 481.58 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Exposure to 1 μM TPOP146 results in a significant decrease of recovery half-life that is comparable to the construct that contained the bromodomain inactivating mutation N1168F, demonstrating that TPOP146 targets the CBP bromodomain in the nucleus and is capable of competing with acetyl-lysine mediated interactions of the CBP bromodomain in cellular environments. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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