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Thalidomide-NH-CH2-COOH

  Cat. No.:  DC42463  
Chemical Structure
927670-97-1
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Field of application
Thalidomide-NH-CH2-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-CH2-COOH can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032.
Cas No.: 927670-97-1
Chemical Name: Thalidomide-NH-CH2-COOH
Synonyms: Glycine,N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-;N-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]glycine (ACI);(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine;2-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-ylamino)acetic acid;2-[[2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino]acetic acid;Thalidomide-NH-CH2-COOH
SMILES: O=C(CNC1C2=C(C(N(C3CCC(=O)NC3=O)C2=O)=O)C=CC=1)O
Formula: C15H13N3O6
M.Wt: 331.280223608017
Purity: >98%
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
Cat. No. Product name Field of application
DC47889 Thalidomide-5-NH2-CH2-COOH Thalidomide-5-NH2-CH2-COOH (compound 114) is a potent and selective inhibitor of tropomyosin receptor kinase (trk). Thalidomide-5-NH2-CH2-COOH is a ligand of E3 ligase. Thalidomide-5-NH2-CH2-COOH has the potential for the treatment of one or more diseases (extracted from patent WO2021170109A1) .
DC47206 Thalidomide-5-CH2-NH2 hydrochloride Thalidomide-5-CH2-NH2 (hydrochloride) is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-CH2-NH2 (hydrochloride) can be connected to the ligand for protein by a linker to form PROTACs.
DC46956 Thalidomide-5-COOH Thalidomide-5-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-COOH can be connected to the ligand for protein by a linker to form PROTACs.
DC42463 Thalidomide-NH-CH2-COOH Thalidomide-NH-CH2-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-CH2-COOH can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032.
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