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Toxoflavin (PKF118-310)

  Cat. No.:  DC10472   Featured
Chemical Structure
84-82-2
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More than 5000 active chemicals with high quality for research!
Field of application
​​Toxoflavin (Xanthothricin)​​ is a dual-function bioactive compound with multimodal therapeutic potential.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 84-82-2
Chemical Name: Toxoflavin
Synonyms: Pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione,1,6-dimethyl-;1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione;TOXOFLAVIN;1,6-Dimethylpyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione (ACI);Pyrimido[5,4-e]-as-triazine-5,7(1H,6H)-dione, 1,6-dimethyl- (7CI, 8CI);1,5,6,7-Tetrahydro-1,6-dimethylpyrimidino[5,4-e]triazine-5,7-dione;K4394;NSC 67078;PKF 118-310;PKF118-310;SID 4251194;Toxoflavine;Xanthothricin;Xanthotricin
SMILES: O=C1N(C)C(=O)C2=NC=NN(C2=N1)C
Formula: C7H7N5O2
M.Wt: 193.162780046463
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: PKF118-310 is an inhibitor of survivin expression and antagonist of Tcf4/b-catenin signaling. Shown to induce apoptosis in tumor cells.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC10472 Toxoflavin (PKF118-310) ​​Toxoflavin (Xanthothricin)​​ is a dual-function bioactive compound with multimodal therapeutic potential.
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DC9880 KYA1797K KYA1797K is a highly potent and selective Wnt/β-catenin inhibitor with IC50 of 0.75 µM (TOPflash assay).
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DC3130 ICG-001 ICG-001 is a small-molecule antagonist of b-catenin/TCF-mediated transcription (IC50 = 3 uM) and specifically downregulates the expression of a subset of b-catenin/TCF-responsive genes. ICG-001 binds specifically to cyclic AMP response element-binding pro
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