Cas No.: | 2225824-53-1 |
Chemical Name: | N-(2-(4-(3-(1,3-dimethyl-1H-indazol-6-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-2-oxoethyl)benzamide |
Synonyms: | YTX465;YTX 465 |
SMILES: | C(NCC(N1CCC(C2ON=C(C3=CC4=C(C=C3)C(C)=NN4C)N=2)CC1)=O)(=O)C1=CC=CC=C1 |
Formula: | C25H26N6O3 |
M.Wt: | 458.522 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | YTX-465 (YTX465) is a specific small molecule that rescues yeast from a-Syn cytotoxicity with EC50 of 15 nM, via inhibiting Ole1, the yeast homolog of human stearoyl-CoA desaturase (SCD); YTX-465 is inactive at SCD1. |
Target: | SCD |
References: | References 1. Vincent BM, et al. Cell Rep. 2018 Dec 4;25(10):2742-2754.e31. View Related Products by Target Stearoyl-CoA Desaturase (SCD) |