AD-5467|CAS 112808-22-7|DC Chemicals

Cas No.:	112808-22-7
Chemical Name:	AD-5467
Formula:	C₁₆H₂₁NO₃S
M.Wt:	307.41
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC79602	M 16209	M 16209 is an orally active aldose reductase (AR) inhibitor. M 16209 inhibits partially purified AR from various sources with IC50 values of 0.12, 0.24, 4.5, 1.2 and 9.3 μM for rat lens AR, bovine lens AR, bovine kidney AR, canine lens AR and human placental AR. M 16209 can be used for the research of metabolic disease, such as diabetes.
DC79185	AD-5467	AD-5467 is a potent and selective aldose reductase inhibitor. AD-5467 exhibits antidiabetic effect. AD-5467 can be used for the research of metabolic disease, such as diabetes.
DC79103	Populin	Populin (Populoside) is a phenolic glucoside with antioxidant activities. Populin inhibits aldose reductase with an IC50 of 18.55 μM. Populin shows IC50s of 6.76 µM and 1.69 mM in DPPH radical-scavenging and ABTS ·+ radical-scavenging assays. Populin also inhibits D-Sorbitol accumulation.Populin has the potential to be used in the study of diabetic complications.
DC78211	AKR1B1/STAT3/SLC7A11-regulator-1	AKR1B1/STAT3/SLC7A11-regulator-1 (5a) is an AKR1B1/STAT3/SLC7A11 regulator that reverses DOX resistance in MCF-7/ADR cells by enhancing ferroptosis activity. AKR1B1/STAT3/SLC7A11-regulator-1 can be used in breast cancer research.
DC76824	WF-3681	WF-3681 (compound 1) is an aldose reductase inhibitor and a fungal metabolite.
DC76823	RJG-2051	RJG-2051 is a selective covalent aldo-keto reductase family 1 member C3 (AKR1C3) inhibitor with an IC50 value of 13 nM. RJG-2051 interferes with the metabolic process of substrates such as androgens, estrogens, and prostaglandins by AKR1C3. RJG-2051 is promising for research of cancers.
DC76822	M79175	M79175 is an aldose reductase inhibitor that can be used in the study of early diabetic retinopathy.
DC76821	(Rac)-Fidarestat	(Rac)-Fidarestat ((Rac)-SNK 860) is the racemate of Fidarestat-resistant hepatitis B.
DC73712	Imirestat	Imirestat (AL-1576) is a potent aldose reductase inhibitor with IC50 of 8.5 nM for rat lens aldose reductase, with similar IC50 value for the human placental enzyme, shows high affinity for AKR1A1 and AKR1B1 with Ki of 47 and 46 nM respectively.
DC73711	BAY1128688	BAY1128688 is a potent, steroidal aldo-keto reductase 1C3 (AKR1C3) inhibitor with potential for endometriosis.