Cas No.: | 1403787-62-1 |
Chemical Name: | Bepirovirsen |
Synonyms: | Bepirovirsen |
Purity: | >95% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Target: | HBV RNA |
In Vivo: | Bepirovirsen (22-50 mg/kg/week; s.c. twice weekly for week 1 and once weekly for weeks 2-4) reduces hepatic HBV RNA and DNA in HBV-transgenic mice. |
In Vitro: | Bepirovirsen (16-250 nM; 16 h) reduces hepatitis B virus (HBV) RNA, DNA, and viral proteins in HepG2.2.15 cells. |